Diagnostik der Duftstoffallergie

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• 作者：Prof. Dr. J. Geier ; W. Uter
• 关键词：Duftstoff ; Mix ; Epikutantestung ; Falsch positive Reaktionen ; Einzelstoffe ; Kontaktallergen ; Fragrance mix ; False ; positive reactions ; Patch tests ; Individual substances ; Contact allergens
• 刊名：Der Hautarzt
• 出版年：2015
• 出版时间：September 2015
• 年：2015
• 卷：66
• 期：9
• 页码：674-679
• 全文大小：475 KB
• 参考文献：1.Andersch Bj?rkman Y, Hagvall L, Siwmark C, Niklasson B, Karlberg AT, Br?red Christensson J (2014) Air-oxidized linalool elicits eczema in allergic patients - a repeated open application test study. Contact Dermatitis 70:129-38CrossRef PubMed
  2.Api AM (2006) Only Peru Balsam extracts or distillates are used in perfumery. Contact Dermatitis 54:179CrossRef PubMed
  3.Api AM, Vey M (2010) A new IFRA Standard on the fragrance ingredient, hydroxyisohexyl 3-cyclohexene carboxaldehyde. Contact Dermatitis 62:254-55CrossRef PubMed
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  5.Christensson JB, Hellsén S, B?rje A, Karlberg AT (2014) Limonene hydroperoxide analogues show specific patch test reactions. Contact Dermatitis 70:291-99CrossRef PubMed
  6.Frosch PJ, Geier J, Uter W, Goossens A (2011) Patch Testing with the Patients-Own Products. In: Johansen JD, Frosch PJ, Lepoittevin JP (Hrsg) Contact Dermatitis, 5.?Aufl. Springer, Berlin, S?1107-119CrossRef
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  8.Frosch PJ, Pirker C, Rastogi SC, Andersen KE, Bruze M, Svedman C, Goossens A, White IR, Uter W, Arnau EG, Lepoittevin JP, Menné T, Johansen JD (2005) Patch testing with a new fragrance mix detects additional patients sensitive to perfumes and missed by the current fragrance mix. Contact Dermatitis 52:207-15CrossRef PubMed
  9.Geier J, Schnuch A, Lessmann H, Uter W (2015) Reactivity to sorbitan sesquioleate affects reactivity to fragrance mix I. Contact Dermatitis (accepted for publication)
  10.Geier J, Uter W, Lessmann H, Schnuch A (2015) Fragrance mix I and II: results of breakdown tests. Flavour Fragr J 30:264-74
  11.Hausen BM (1996) Perubalsam. In: Hausen BM, Brinkmann J, Dohn W (Hrsg) Lexikon der Kontaktallergene. 3. Erg?nzungslieferung 1996. Ecomed Verlag, Landsberg am Lech, P9, S?1-3
  12.Hausen BM (2001) Contact allergy to Balsam of Peru. II. Patch test results in 102 patients with selected Balsam of Peru constituents. Am J Contact Dermat 12:93-02PubMed
  13.IFRA standard Oakmoss extracts, IFRA standard Isoeugenol. http://?www.?ifraorg.?org/?en-us/?standards-library . Zugegriffen: 20. Mai 2015
  14.Karlberg AT, B?rje A, Duus Johansen J, Lidén C, Rastogi S, Roberts D, Uter W, White IR (2013) Activation of non-sensitizing or low-sensitizing fragrance substances into potent sensitizers -prehaptens and prohaptens. Contact Dermatitis 69:323-34CrossRef PubMed
  15.Mahler V, Geier J, Schnuch A (2014) Neue Entwicklungen zum Thema Epikutantest -aktuelle Daten aus der Deutschen Kontaktallergie-Gruppe (DKG) und Informationsverbund Dermatologischer Kliniken (IVDK). J Dtsch Dermatol Ges 12:583-94CrossRef PubMed
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  17.Schnuch A, Geier J, Uter W (2012) Is hydroxyisohexyl 3-cyclohexene carboxaldehyde sensitisation declining in central Europe? Contact Dermatitis 67:47-9CrossRef PubMed
  18.Schnuch A, Uter W, Geier J, Lessmann H, Frosch PJ (2007) Sensitization to 26 fragrances to be labelled according to current European regulation. Results of the IVDK and review of the literature. Contact Dermatitis 57:1-0CrossRef PubMed
  19.Uter W, Aberer W, Armario-Hita JC, Fernandez-Vozmediano JM, Ayala F, Balato A, Bauer A, Ballmer-Weber B, Beliauskiene A, Fortina AB, Bircher A, Brasch J, Chowdhury MM, Coenraads PJ, Schuttelaar ML, Cooper S, Czarnecka-Operacz M, Zmudzinska M, Elsner P, English JS, Frosch PJ, Fuchs T, García-Gavín J, Fernández-Redondo V, Gawkrodger DJ, Giménez-Arnau A, Green CM, Horne HL, Johansen JD, Jolanki R, Pesonen M, King CM, Krêcisz B, Chomiczewska D, Kiec-Swierczynska M, Larese F, Mahler V, Ormerod AD, Peserico A, Rantanen T, Rustemeyer T, Sánchez-Pérez J, Sansom JE, Silvestre JF, Simon D, Spiewak R, Statham BN, Stone N, Wilkinson M, Schnuch A (2012) Current patch test results with the European baseline series and extensions to it from the ?European Surveillance System on Contact Allergy-network, 2007-008. Contact Dermatitis 67:9-9CrossRef PubMed
  20.Uter W, Johansen JD, B?rje A, Karlberg AT, Lidén C, Rastogi S, Roberts D, White IR (2013) Categorization of fragrance contact allergens for prioritization of preventive measures: clinical and experimental data and consideration of structure-activity relationships. Contact Dermatitis 69:196-30CrossRef PubMed
  21.Uter W, Schmidt E, Geier J, Lessmann H, Schnuch A, Frosch PJ (2010) Contact allergy to essential oils: current patch test results (2000
• 作者单位：Prof. Dr. J. Geier (1)
  W. Uter (2)
  
  1. Informationsverbund Dermatologischer Kliniken, Institut an der Universit?t G?ttingen, Universit?tsmedizin G?ttingen, Von-Bar-Str. 2-4, 37073, G?ttingen, Deutschland
  2. Institut für Medizininformatik, Biometrie und Epidemiologie, Friedrich-Alexander-Universit?t Erlangen-Nürnberg, Erlangen, Deutschland
  
• 刊物主题：Dermatology; Immunology; Allergology; Proctology;
• 出版者：Springer Berlin Heidelberg
• ISSN：1432-1173

文摘

The diagnostic workup of contact allergy to fragrances must not be limited to patch testing with the two well-established fragrance mixes. False-positive reactions to these mixes occur in up to 50- of the patch tested patients. For the diagnostic work-up of positive reactions, and in cases of suspected fragrance allergy, patch testing with the single mix components and additional fragrances is mandatory. Frequently sensitizing fragrance materials are the 14 components of the two fragrance mixes and tree moss (Evernia furfuracea), ylang ylang oil (I + II; Cananga odorata), lemongrass oil (Cymbopogon schoenanthus), sandalwood oil (Santalum album), jasmine absolute (Jasminum spp.), and, less frequently, clove oil (Eugenia caryophyllus), cedarwood oil (Cedrus atlantica/deodara, Juniperus virginiana), Neroli oil (Citrus aurantium amara flower oil), salicylaldehyde, narcissus absolute (Narcissus spp.), and patchouli oil (Pogostemon cablin). Keywords Fragrance mix False-positive reactions Patch tests Individual substances Contact allergens