Dehydrogenation of 1-aryl(hetaryl)-1,2,3,4-tetrahydro-9H-β-carboline-3-carboxylic acids and their esters with dimethyl sulfoxide

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• 作者：M. G. Abramyants ; D. A. Lomov ; T. I. Zavyazkina
• 刊名：Russian Journal of Organic Chemistry
• 出版年：2016
• 出版时间：November 2016
• 年：2016
• 卷：52
• 期：11
• 页码：1610-1615
• 全文大小：
• 刊物主题：Organic Chemistry;
• 出版者：Pleiades Publishing
• ISSN：1608-3393
• 卷排序：52

文摘

Oxidative dehydrogenation of 1-aryl(hetaryl)-1,2,3,4-tetrahydro-9Н-β-carboline-3-carboxylic acids derivatives with dimethyl sulfoxide leads to the formation of 1-aryl(hetaryl)-9Н-β-carbolines. Simultaneously with the dehydrogenation decarboxylation occurs. At the oxidation with dimethyl sulfoxide of methyl 1-aryl (hetaryl)-1,2,3,4-tetrahydro-9Н-β-carboline-3-carboxylicates methyl 1-aryl(hetaryl)-9Н-β-carboline-3-carboxylates formed whose hydrolysis afforded the corresponding 1-aryl(hetaryl)-9Н-β-carboline-3-carboxylic acids.