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作者单位:Sander Land (19) Steve Niederer (19) Pablo Lamata (19) (20)
19. Department of Biomedical Engineering, King鈥檚 College London, London, UK 20. Deptartment of Computer Science, University of Oxford, Oxford, UK
丛书名:Statistical Atlases and Computational Models of the Heart - Imaging and Modelling Challenges
ISBN:978-3-319-14678-2
刊物类别:Computer Science
刊物主题:Artificial Intelligence and Robotics Computer Communication Networks Software Engineering Data Encryption Database Management Computation by Abstract Devices Algorithm Analysis and Problem Complexity
出版者:Springer Berlin / Heidelberg
ISSN:1611-3349
文摘
An accurate estimation of myocardial stiffness and decaying active tension is critical for the characterization of the diastolic function of the heart. Computational cardiac models can be used to analyse deformation and pressure data from the left ventricle in order to estimate these diastolic metrics. The results of this methodology depend on several model assumptions. In this work we reveal a nominal impact of the choice of myocardial fibre orientation between a rule-based description and personalised approach based on diffusion-tensor magnetic resonance imaging. This result suggests the viability of simplified clinical imaging protocols for the model-based estimation of diastolic biomarkers.