Cardiac effects of seasonal ambient particulate matter and ozone co-exposure in rats

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• 作者：Aimen K Farraj ; Leon Walsh ; Najwa Haykal-Coates…
• 关键词：Ambient particulate matter ; Ozone ; Season ; Cardiac ; Health effects ; Co ; exposure ; Electrocardiogram ; Rats ; Source apportionment ; Elements
• 刊名：Particle and Fibre Toxicology
• 出版年：2015
• 出版时间：December 2015
• 年：2015
• 卷：12
• 期：1
• 全文大小：1,908 KB
• 刊物主题：Pharmacology/Toxicology; Pneumology/Respiratory System; Nanotechnology and Microengineering;
• 出版者：BioMed Central
• ISSN：1743-8977

文摘

Background The potential for seasonal differences in the physicochemical characteristics of ambient particulate matter (PM) to modify interactive effects with gaseous pollutants has not been thoroughly examined. The purpose of this study was to compare cardiac responses in conscious hypertensive rats co-exposed to concentrated ambient particulates (CAPs) and ozone (O₃) in Durham, NC during the summer and winter, and to analyze responses based on particle mass and chemistry.