High Resolution Extraction of Local Human Cardiac Fibre Orientations
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  • 作者:Fran?ois Varray (19) (20)
    Lihui Wang (19) (20)
    Laurent Fanton (19) (20)
    Yue-Min Zhu (19) (20)
    Isabelle E. Magnin (19) (20)
  • 关键词:ESRF ; DTMRI ; myocytes arrangement ; cardiac fibre
  • 刊名:Lecture Notes in Computer Science
  • 出版年:2013
  • 出版时间:2013
  • 年:2013
  • 卷:7945
  • 期:1
  • 页码:158-165
  • 全文大小:2217KB
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  • 作者单位:Fran?ois Varray (19) (20)
    Lihui Wang (19) (20)
    Laurent Fanton (19) (20)
    Yue-Min Zhu (19) (20)
    Isabelle E. Magnin (19) (20)

    19. CNRS UMR 5220, INSERM U1044, INSA-Lyon, Creatis, Université de Lyon, France
    20. Université Lyon 1, 7 av Jean Capelle, 69621, Villeurbanne, France
  • ISSN:1611-3349
文摘
Diffusion tensor magnetic resonance imaging (DTMRI) is usually used to detect the displacement distribution of water molecules in biological structure. However, in post-mortem heart fibre imaging, the low spatial resolution does not allow investigating the cardiac fibre structure at microscopic scale. In this paper, the myocyte arrangement of a human heart is investigated at a high resolution of 3.5?μm using the European Synchrotron Radiation Facility (ESRF). The orientation of the myocytes is then computed and extracted at various depths of the heart sample with a multi-scale approach. The helix arrangement of the fibre is obtained at a higher resolution compared to DTMRI. The results show that the measured elevation angles are in good agreement with knowledge of cardiac muscle anatomy. Such high-resolution cardiac fibre orientation information can be used to validate DTMRI measurements and analyze the evolution of cardiac fibre orientations from microscopic level to macroscopic one.

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