文摘
Diffusion tensor magnetic resonance imaging (DTMRI) is usually used to detect the displacement distribution of water molecules in biological structure. However, in post-mortem heart fibre imaging, the low spatial resolution does not allow investigating the cardiac fibre structure at microscopic scale. In this paper, the myocyte arrangement of a human heart is investigated at a high resolution of 3.5?μm using the European Synchrotron Radiation Facility (ESRF). The orientation of the myocytes is then computed and extracted at various depths of the heart sample with a multi-scale approach. The helix arrangement of the fibre is obtained at a higher resolution compared to DTMRI. The results show that the measured elevation angles are in good agreement with knowledge of cardiac muscle anatomy. Such high-resolution cardiac fibre orientation information can be used to validate DTMRI measurements and analyze the evolution of cardiac fibre orientations from microscopic level to macroscopic one.