Intramuscular injection of human umbilical cord-derived mesenchymal stem cells improves cardiac function in dilated cardiomyopathy rats
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- 作者：Chenggang Mao ; Xu Hou ; Benzhen Wang ; Jingwei Chi…
- 关键词：Mesenchymal stem cells (MSCs) ; Dilated cardiomyopathy (DCM) ; Intramuscular injection ; Cardiac function ; Paracrine
- 刊名：Stem Cell Research & Therapy
- 出版年：2017
- 出版时间：December 2017
- 年：2017
- 卷：8
- 期：1
- 全文大小：3383KB
- 刊物主题：Stem Cells; Cell Biology;
- 出版者：BioMed Central
- ISSN：1757-6512
- 卷排序：8
文摘
BackgroundStem cells provide a promising candidate for the treatment of the fatal pediatric dilated cardiomyopathy (DCM). This study aimed to investigate the effects of intramuscular injection of human umbilical cord-derived mesenchymal stem cells (hUCMSCs) on the cardiac function of a DCM rat model.