T-cell lymphomas, a challenging disease: types, treatments, and future
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- 作者：Helen Ma ; Maher Abdul-Hay
- 关键词：Adult T ; cell leukemia/lymphoma ; Angioimmunoblastic T ; cell lymphoma ; Anaplastic large cell lymphoma ; NK/T ; cell lymphoma ; Cutaneous T ; cell lymphoma ; Novel agents
- 刊名：International Journal of Clinical Oncology
- 出版年：2017
- 出版时间：February 2017
- 年：2017
- 卷：22
- 期：1
- 页码：18-51
- 全文大小：
- 刊物类别：Medicine
- 刊物主题：Oncology; Surgical Oncology; Cancer Research;
- 出版者：Springer Japan
- ISSN：1437-7772
- 卷排序：22
文摘
T-cell lymphomas are rare and aggressive malignancies associated with poor outcome, often because of the development of resistance in the lymphoma against chemotherapy as well as intolerance in patients to the established and toxic chemotherapy regimens. In this review article, we discuss the epidemiology, pathophysiology, current standard of care, and future treatments of common types of T-cell lymphomas, including adult T-cell leukemia/lymphoma, angioimmunoblastic T-cell lymphoma, anaplastic large-cell lymphoma, aggressive NK/T-cell lymphoma, and cutaneous T-cell lymphoma.