Identifying the palliative care needs of patients living with cerebral tumors and metastases: a retrospective analysis

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• 作者：Teneille E. Gofton (1) tgofton@uwo.ca
  Jerome Graber (2)
  Alan Carver (2)
• 关键词：Primary brain tumor &#8211 ; Metastatic tumor &#8211 ; Palliative care &#8211 ; End of life care &#8211 ; Clinical neurology
• 刊名：Journal of Neuro-Oncology
• 出版年：2012
• 出版时间：July 2012
• 年：2012
• 卷：108
• 期：3
• 页码：527-534
• 全文大小：307.6 KB
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• 作者单位：1. Division of Medicine, Department of Pain and Palliative Care, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA2. Department of Neurology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA
• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Oncology
  
• 出版者：Springer Netherlands
• ISSN：1573-7373

文摘

Primary tumors and metastatic involvement of the central nervous system (CNS) lead to a multitude of symptoms and care needs. Patients and caregivers struggle with physical and psychological impairments, a shortened life expectancy and diverse palliative care needs. This study assesses the symptom burden and palliative care needs of patients with primary brain tumors and with metastatic brain tumors requiring inpatient hospital care. It is a retrospective analysis of patients with primary CNS tumors or cerebral metastases over a 6 month period. The data analysed included physical symptom burden and end of life care decisions such as health care proxy, transition to hospice and do-not-resuscitate orders. Hundred and sixty eight patients were included. The most common symptoms were gait impairment (65.5 %), cognitive/personality change (61.9 %), motor deficits (58.3 %), seizures (57.1 %) and delirium (27.4 %). Of the patients that died, 79 % had an appointed health care proxy, 79 % had hospice discussions, 70 % had a do-not-resuscitate order and 24 % received cancer directed therapy in the last month of life. There is a role for more aggressive palliative care support in patients living with primary or metastatic brain tumors.