Frequency of Chlamydia trachomatis infection in cervical intraepithelial lesions and the status of cytological p16/Ki-67 dual-staining

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• 作者：R. Robial ; A. Longatto-Filho ; C. M. Roteli-Martins…
• 关键词：Chlamydia ; Cervical cancer ; Immunocytochemistry ; ki 67
• 刊名：Infectious Agents and Cancer
• 出版年：2017
• 出版时间：December 2017
• 年：2017
• 卷：12
• 期：1
• 全文大小：470KB
• 刊物主题：Cancer Research; Infectious Diseases; Oncology; Tropical Medicine;
• 出版者：BioMed Central
• ISSN：1750-9378
• 卷排序：12

文摘

BackgroundChlamydia trachomatis (Ct) is not a disease subject to mandatory reporting in Brazil, and the prevalence rate of this genital infection varies according to the region in which studies are conducted, as well as by the detection technique employed. Ct has been associated with persistence of Human papillomavirus (HPV) infection and the facilitation of cervical carcinoma development. We evaluated the Chlamydia trachomatis infection and its association with cytology, p16/Ki-67 dual-stained cytology and cervical intraepithelial lesions status in a screening cohort in Brazil.