Paradoxical embolism causing acute embolic events in a patient with hereditary thrombophilia

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• 作者：L. Tang (1)
  Z.F. Fang (1)
  S.H. Zhou (1)
  
  1. Department of Cardiology ; The Second Xiangya Hospital of Central South University ; Middle Ren-Min road No. 139 ; 410011 ; Changsha ; Hunan ; China
  
• 关键词：Paradoxical embolism ; Hereditary thrombophilia ; Multiorgan involvement ; Atrial septal defect ; Warfarin ; Paradoxe Embolie ; Heredit盲re Thrombophilie ; Multiorganbeteiligung ; Vorhofseptumdefekt ; Warfarin
• 刊名：Herz
• 出版年：2015
• 出版时间：April 2015
• 年：2015
• 卷：40
• 期：2
• 页码：314-317
• 全文大小：437 KB
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• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Cardiology
  
• 出版者：Urban & Vogel
• ISSN：1615-6692

文摘

Paradoxical embolism (PDE) is an uncommon but clinically important entity. In clinical practice, PDE involving multiple organs is a rarely reported occurrence. Herein, we present a case of acute pulmonary embolism complicated by PDE through an atrial septal defect (ASD) causing a series of embolic events. Subsequent laboratory screening confirmed the patient to be a heterozygous carrier of the factor V Leiden mutation that increases the risk for deep venous thrombosis (DVT). The patient was treated with warfarin indefinitely and underwent transcatheter ASD closure and implantation of an inferior vena cava filter.