Blood chemokine profile in untreated early rheumatoid arthritis: CXCL10 as a disease activity marker
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- 作者：Jayesh M. Pandya ; Anna-Carin Lundell ; Kerstin Andersson…
- 关键词：Chemokine ; Chemokine receptor ; CXCL10 ; T cell ; Rheumatoid arthritis ; Multivariate discriminant analysis
- 刊名：Arthritis Research & Therapy
- 出版年：2017
- 出版时间：December 2017
- 年：2017
- 卷：19
- 期：1
- 全文大小：1446KB
- 刊物主题：Rheumatology; Orthopedics;
- 出版者：BioMed Central
- ISSN：1478-6362
- 卷排序：19
文摘
BackgroundWe have recently analyzed the profile of T-cell subtypes based on chemokine receptor expression in blood from untreated early rheumatoid arthritis (ueRA) patients compared to healthy controls (HC). Here, we compared the levels of the respective chemokines in blood plasma of ueRA patients with those of HC. We also studied the association of chemokine levels with the proportions of circulating T-cell subsets and the clinical disease activity.