文摘
Zusanli (ST-36) is one of the four most important acupoints in traditional Chinese medicine because it is believed to co-ordinate the functions of the immunological and gastrointestinal systems. We test the hypothesis that acupuncture at Zusanli may have significant impact on peripheral blood flow and autonomic activities by computing the area under the pulse volume curves and heart rate variability from data acquired through non-invasive approaches of eight-channel photoplethysmography and electrocardiography (ECG), respectively, from 28 healthy young adults (22 males, 6 females). Moreover, the complexity of physiological signals was compared in terms of multiscale entropy (MSE) and short-time MSE (sMSE) before and after acupuncture. The results demonstrate significant elevation of peripheral blood flow in all subjects during and immediately after acupuncture, suggesting elevated parasympathetic activities. On the other hand, significantly reduced sympathetic activities were noted in subjects with body mass index (BMI) <25 (n = 18) (p < 0.05). Additionally, MSE analysis of the R–R interval from a 5-min recording of ECG from subjects with BMI < 25 before and immediately after acupuncture showed significantly elevated sMSE immediately after acupuncture. However, no significant difference was noted in MSE between the two time points. In conclusion, the results of this study demonstrate that acupuncture at Zusanli augments systemic parasympathetic activities and peripheral circulation. Furthermore, sMSE revealed increased physiological complexity after acupuncture for individuals with normal weight.KeywordsZusanliAcupunctureMultiscale entropyHeart rate variability