Biomedical electrosurgery devices containing nanostructure for minimally invasive surgery: reduction of thermal injury and acceleration of wound healing for liver cancer

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• 作者：Wen-Tien Hsiao (1) (2) (3)
  Li-Hsiang Lin (2) (3)
  Hsi-Jen Chiang (3) (4) (5)
  Keng-Liang Ou (3) (5) (6) (7)
  Han-Yi Cheng (3) (6) (7)
  
• 刊名：Journal of Materials Science Materials in Medicine
• 出版年：2015
• 出版时间：February 2015
• 年：2015
• 卷：26
• 期：2
• 全文大小：5,001 KB
• 参考文献：1. Duffy S. The tissue and thermal effects of electrosurgery in the uterine cavity. Bailli猫re鈥檚 Clin Obstet Gynaecol. 1995;9(2):261鈥?7. CrossRef
  2. Fine R, Vose J. Traditional electrosurgery and a low thermal injury dissection device yield different outcomes following bilateral skin-sparing mastectomy: a case report. J Med Case Rep. 2011;5(1):1鈥?. CrossRef
  3. Zhang GY, Zhou XF, Zhou XY, Wen QY, You BG, Liu Y, Zhang XN, Jin Y. Effect of alginate-chitosan sustained release microcapsules for transhepatic arterial embolization in VX2 rabbit liver cancer model. J Biomed Mater Res Part A. 2013;101(11):3192鈥?00.
  4. Koch C, Friedrich T, Metternich F, Tannapfel A, Reimann H-P, Eichfeld U. Determination of temperature elevation in tissue during the application of the harmonic scalpel. Ultrasound Med Biol. 2003;29(2):301鈥?. CrossRef
  5. Sutton PA, Awad S, Perkins AC, Lobo DN. Comparison of lateral thermal spread using monopolar and bipolar diathermy, the Harmonic Scalpel鈩?and the Ligasure鈩? Br J Surg. 2010;97(3):428鈥?3. CrossRef
  6. Chan YH, Huang CF, Ou KL, Peng PW. Mechanical properties and antibacterial activity of copper doped diamond-like carbon films. Surf Coat Technol. 2011;206(6):1037鈥?0. CrossRef
  7. Al-Sukhun J, Kelleway J, Helenius M. Development of a three-dimensional finite element model of a human mandible containing endosseous dental implants. I. Mathematical validation and experimental verification. J Biomed Mater Res Part A. 2007;80A(1):234鈥?6. CrossRef
  8. Al-Sukhun J, Lindqvist C, Helenius M. Development of a three-dimensional finite element model of a human mandible containing endosseous dental implants. II. Variables affecting the predictive behavior of a finite element model of a human mandible. J Biomed Mater Res Part A. 2007;80A(1):247鈥?6. CrossRef
  9. Cheng HY, Hsiao WT, Lin LH, Hsu YJ, Sinrang AW, Ou KL. Effects of antibacterial nanostructured composite films on vascular stents: hemodynamic behaviors, microstructural characteristics, and biomechanical properties. J Biomed Mater Res Part A. 2014;103:269鈥?5. CrossRef
  10. Cheng HY, Chu KT, Shen FC, Pan YN, Chou HH, Ou KL. Stress effect on bone remodeling and osseointegration on dental implant with novel nano/microporous surface functionalization. J Biomed Mater Res Part A. 2013;101A(4):1158鈥?4. CrossRef
  11. Cheng HY, Peng PW, Lin YJ, Chang ST, Pan YN, Lee SC, Ou KL, Hsu WC. Stress analysis during jaw movement based on vivo computed tomography images from patients with temporomandibular disorders. Int J Oral Maxillofac Surg. 2013;42(3):386鈥?2. CrossRef
  12. Chu KT, Cheng HY, Pan YN, Chen SY, Ou KL. Enhancement of biomechanical behavior on osseointegration of implant with SLAffinity. J Biomed Mater Res Part A. 2013;101A(4):1195鈥?00. CrossRef
  13. Ward AK, Ladtkow CM, Collins GJ. Material removal mechanisms in monopolar electrosurgery. in Engineering in medicine and biology society, 2007. EMBS 2007. 29th Annual International Conference of the IEEE, 2007.
  14. Olaya JJ, Rodil SE, Muhl S, S谩nchez E. Comparative study of chromium nitride coatings deposited by unbalanced and balanced magnetron sputtering. Thin Solid Films. 2005;474(1鈥?):119鈥?6. CrossRef
  15. Dos Santos I, Haemmerich D, Pinheiro C, Da Rocha A. Effect of variable heat transfer coefficient on tissue temperature next to a large vessel during radiofrequency tumor ablation. Biomed Eng Online. 2008;7(1):21. CrossRef
  16. Savvides N, Bell TJ. Hardness and elastic modulus of diamond and diamond-like carbon films. Thin Solid Films. 1993;228(1鈥?):289鈥?2. CrossRef
  17. Ledbetter HM, Frederick NV, Austin MW. Elastic-constant variability in stainless-steel 304. J Appl Phys. 1980;51(1):305鈥?. CrossRef
  18. Elliott-Lewis EW, Mason AM, Barrow DL. Evaluation of a new bipolar coagulation forceps in a thermal damage assessment. Neurosurgery. 2009;65(6):1182鈥? discussion 1187. CrossRef
  19. Moffitt TP, Baker DA, Kirkpatrick SJ, Prahl SA. Mechanical properties of coagulated albumin and failure mechanisms of liver repaired with the use of an argon-beam coagulator with albumin. J Biomed Mater Res. 2002;63(6):722鈥?. CrossRef
  20. Burns RL, Carruthers A, Langtry JA, Trotter MJ. Electrosurgical skin resurfacing: a new bipolar instrument. Dermatol Surg. 1999;25(7):582鈥?. CrossRef
  21. Wright TCJ, Gagnon S, Richart RM, Ferenczy A. Treatment of cervical intraepithelial neoplasia using the loop electrosurgical excision procedure. Obstet Gynecol. 1992;79(2):173鈥?.
  22. Habermann W, M眉ller W. Tissue penetration of bipolar electrosurgical currents: Joule overheating beyond the surface layer. Head Neck. 2013;35(4):535鈥?0. CrossRef
  23. Hensman C, Baty D, Willis RG, Cuschieri A. Chemical composition of smoke produced by high-frequency electrosurgery in a closed gaseous environment. Surg Endosc. 1998;12(8):1017鈥?. CrossRef
  24. Munro MG, Weisberg M, Rubinstein E. Gas and air embolization during hysteroscopic electrosurgical vaporization: comparison of gas generation using bipolar and monopolar electrodes in an experimental model. J Am Assoc Gynecol Laparosc. 2001;8(4):488鈥?4. CrossRef
  25. Chen HY, Tsai CJ, Lu FH. The Young鈥檚 modulus of chromium nitride films. Surf Coat Technol. 2004;184(1):69鈥?3. CrossRef
  26. Mikami T, Takahashi A, Hashi K, Gasa S, Houkin K. Performance of bipolar forceps during coagulation and its dependence on the tip material: a quantitative experimental assay. J Neurosurg. 2004;100(1):133鈥?. CrossRef
  27. Sevimay M, Turhan F, Kili莽arslan MA, Eskitascioglu G. Three-dimensional finite element analysis of the effect of different bone quality on stress distribution in an implant-supported crown. J Prosthet Dent. 2005;93(3):227鈥?4. CrossRef
  28. Tanaka E, Tanne K, Sakuda M. A three-dimensional finite element model of the mandible including the TMJ and its application to stress analysis in the TMJ during clenching. Med Eng Phys. 1994;16(4):316鈥?2. CrossRef
  
• 作者单位：Wen-Tien Hsiao (1) (2) (3)
  Li-Hsiang Lin (2) (3)
  Hsi-Jen Chiang (3) (4) (5)
  Keng-Liang Ou (3) (5) (6) (7)
  Han-Yi Cheng (3) (6) (7)
  
  1. Department of Diagnostic Radiology, Taipei Medical University Hospital, Taipei, 110, Taiwan
  2. School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei, 110, Taiwan
  3. Research Center for Biomedical Devices and Prototyping Production, Taipei Medical University, Taipei, Taiwan
  4. School of Dental Technology, Taipei Medical University, No. 250 Wu-Hsing Street, Taipei, 110, Taiwan
  5. Department of Dentistry, Taipei Medical University-Shuang Ho Hospital, Taipei, 235, Taiwan
  6. Graduate Institute of Biomedical Materials and Tissue Engineering, Taipei Medical University, Taipei, 110, Taiwan
  7. Research Center for Biomedical Implants and Microsurgery Devices, Taipei Medical University, Taipei, 110, Taiwan
  
• 刊物类别：Chemistry and Materials Science
• 刊物主题：Chemistry
  Biomaterials
  Characterization and Evaluation Materials
  Polymer Sciences
  Metallic Materials
  Ceramics,Glass,Composites,Natural Materials
  Surfaces and Interfaces and Thin Films
  
• 出版者：Springer Netherlands
• ISSN：1573-4838

文摘

The aim of the present study was to investigate the thermal injury in the liver after a minimally invasive electrosurgery technique with a copper-doped diamond-like carbon (DLC-Cu) surface coating. To effectively utilize electrosurgery in a clinical caner setting, it is necessary to suppress the thermal injury to adjacent tissues. The surface morphologies of DLC-Cu thin films were characterized using scanning electron microscopy and transmission electron microscopy. Three-dimensional liver models were reconstructed using magnetic resonance imaging to simulate the electrosurgical procedure. Our results indicated that the temperature decreased significantly when minimally electrosurgery with nanostructured DLC-Cu thin films was used, and that it continued to decrease with increasing film thickness. In an animal model, thermography revealed that the surgical temperature was significantly lower in the minimally invasive electrosurgery with DLC-Cu thin film (DLC-Cu-SS) compared to untreated electrosurgery. In addition, DLC-Cu-SS created a relatively small thermal injury area and lateral thermal effect. These results indicated that the biomedical nanostructure coating reduced excessive thermal injury, and uniformly distributed temperature in the liver.