Breastfeeding for reducing the risk of pneumonia morbidity and mortality in children under two: a systematic literature review and meta-analysis

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• 作者：Laura M Lamberti (57)
  Irena Zakarija-Grkovi? (58)
  Christa L Fischer Walker (57)
  Evropi Theodoratou (59)
  Harish Nair (59) (60)
  Harry Campbell (59)
  Robert E Black (57)
  
• 刊名：BMC Public Health
• 出版年：2013
• 出版时间：September 2013
• 年：2013
• 卷：13
• 期：3-supp
• 全文大小：
• 作者单位：Laura M Lamberti (57)
  Irena Zakarija-Grkovi? (58)
  Christa L Fischer Walker (57)
  Evropi Theodoratou (59)
  Harish Nair (59) (60)
  Harry Campbell (59)
  Robert E Black (57)
  
  57. Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
  58. Department of Family Medicine, University of Split School of Medicine, Split, Croatia
  59. Centre of Population Health Sciences, University of Edinburgh Medical School, Edinburgh, UK
  60. Public Health Foundation of India, New Delhi, India
  
• ISSN：1471-2458

文摘

Background Suboptimal breastfeeding practices among infants and young children <24 months of age are associated with elevated risk of pneumonia morbidity and mortality. We conducted a systematic review and meta-analysis to quantify the protective effects of breastfeeding exposure against pneumonia incidence, prevalence, hospitalizations and mortality. Methods We conducted a systematic literature review of studies assessing the risk of selected pneumonia morbidity and mortality outcomes by varying levels of breastfeeding exposure among infants and young children <24 months of age. We used random effects meta-analyses to generate pooled effect estimates by outcome, age and exposure level. Results Suboptimal breastfeeding elevated the risk of pneumonia morbidity and mortality outcomes across age groups. In particular, pneumonia mortality was higher among not breastfed compared to exclusively breastfed infants 0-5 months of age (RR: 14.97; 95% CI: 0.67-332.74) and among not breastfed compared to breastfed infants and young children 6-23 months of age (RR: 1.92; 95% CI: 0.79-4.68). Conclusions Our results highlight the importance of breastfeeding during the first 23 months of life as a key intervention for reducing pneumonia morbidity and mortality.