Robot-Assisted Passive Exercise for Ankle Hypertonia in Individuals with Chronic Spinal Cord Injury

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• 作者：Chia-Ying Fang ; Miao-Ju Hsu ; Chih-Chung Chen…
• 关键词：Hypertonia ; Stretch reflex ; Spinal cord injury
• 刊名：Journal of Medical and Biological Engineering
• 出版年：2015
• 出版时间：August 2015
• 年：2015
• 卷：35
• 期：4
• 页码：464-472
• 全文大小：882 KB
• 参考文献：1.Lundqvist, C., Siosteen, A., Blomstrand, C., Lind, B., & Sullivan, M. (1991). Spinal cord injuries. Clinical, functional, and emotional status. Spine, 16, 78鈥?3.CrossRef
  2.Sosnoff, J. J., Gappmaier, E., Frame, A., & Motl, R. W. (2011). Influence of spasticity on mobility and balance in persons with multiple sclerosis. Journal of Neurologic Physical Therapy, 35, 129鈥?32.CrossRef
  3.Hesse, S., Schulte-Tigges, G., Konrad, M., Bardeleben, A., & Werner, C. (2003). Robot-assisted arm trainer for the passive and active practice of bilateral forearm and wrist movements in hemiparetic subjects. Archives of Physical Medicine and Rehabilitation, 84, 915鈥?20.CrossRef
  4.Fu, L. C., Wang, W. W., Tsai, B. C., Hsu, L. C., & Lai, J. S. (2014). Guidance-control-based exoskeleton rehabilitation robot for upper limbs: Application to circle drawing for physiotherapy and training. Journal of Medical and Biological Engineering, 34(3), 284鈥?92.CrossRef MATH
  5.Hsieh, Y. W., Lin, K. C., Wu, C. Y., Lien, H. Y., Chen, J. L., Chen, C. C., & Chang, W. H. (2014). Predicting clinically significant changes in motor and functional outcomes after robot-assisted stroke rehabilitation. Archives of Physical Medicine and Rehabilitation, 95, 316鈥?21.CrossRef
  6.Wu, C. Y., Liing, R. J., Chen, H. C., Chen, C. L., & Lin, K. C. (2014). Arm and trunk movement kinematics during seated reaching within and beyond arm鈥檚 length in people with stroke: A validity study. Physical Therapy, 94, 845鈥?56.CrossRef
  7.Swinnen, E., Duerinck, S., Baeyens, J. P., Meeusen, R., & Kerckhofs, E. (2010). Effectiveness of robot-assisted gait training in persons with spinal cord injury: A systematic review. Journal of Rehabilitation Medicine, 42, 520鈥?26.CrossRef
  8.Hornby, T. G., Zemon, D. H., & Campbell, D. (2005). Robotic-assisted, body-weight-supported treadmill training in individuals following motor incomplete spinal cord injury. Physical Therapy, 85, 52鈥?6.
  9.Riener, R., Nef, T., & Colombo, G. (2005). Robot-aided neurorehabilitation of the upper extremities. Medical and Biological Engineering and Computing, 43, 2鈥?0.CrossRef
  10.Chang, Y. J., Liang, J. N., Hsu, M. J., Lien, H. Y., Fang, C. Y., & Lin, C. H. (2013). Effects of continuous passive motion on reversing the adapted spinal circuit in humans with chronic spinal cord injury. Archives of Physical Medicine and Rehabilitation, 94, 822鈥?28.CrossRef
  11.Wirz, M., Zemon, D. H., Rupp, R., Scheel, A., Colombo, G., Dietz, V., & Hornby, T. G. (2005). Effectiveness of automated locomotor training in patients with chronic incomplete spinal cord injury: A multicenter trial. Archives of Physical Medicine and Rehabilitation, 86, 672鈥?80.CrossRef
  12.Dobkin, B., Barbeau, H., Deforge, D., Ditunno, J., Elashoff, R., Apple, D., et al. (2007). The evolution of walking-related outcomes over the first 12聽weeks of rehabilitation for incomplete traumatic spinal cord injury: The multicenter randomized Spinal Cord Injury Locomotor Trial. Neurorehabilitation Neural Repair, 21, 25鈥?5.CrossRef
  13.Fleerkotte, B. M., Koopman, B., Buurke, J. H., van Asseldonk, E. H., van der Kooij, H., & Rietman, J. S. (2014). The effect of impedance-controlled robotic gait training on walking ability and quality in individuals with chronic incomplete spinal cord injury: An explorative study. Journal of NeuroEngineering Rehabilitation, 11, 26.CrossRef
  14.Dietz, V., & Fouad, K. (2014). Restoration of sensorimotor functions after spinal cord injury. Brain, 137, 654鈥?67.CrossRef
  15.Cai, L. L., Fong, A. J., Otoshi, C. K., Liang, Y., Burdick, J. W., Roy, R. R., & Edgerton, V. R. (2006). Implications of assist-as-needed robotic step training after a complete spinal cord injury on intrinsic strategies of motor learning. Journal of Neuroscience, 26, 10564鈥?0568.CrossRef
  16.Fong, A. J., Cai, L. L., Otoshi, C. K., Reinkensmeyer, D. J., Burdick, J. W., Roy, R. R., & Edgerton, V. R. (2005). Spinal cord-transected mice learn to step in response to quipazine treatment and robotic training. Journal of Neuroscience, 25, 11738鈥?1747.CrossRef
  17.Katz, R. T., & Rymer, W. Z. (1989). Spastic hypertonia: Mechanisms and measurement. Archives of Physical Medicine and Rehabilitation, 70, 144鈥?55.
  18.Dietz, V., & Berger, W. (1983). Normal and impaired regulation of muscle stiffness in gait: A new hypothesis about muscle hypertonia. Experimental Neurology, 79, 680鈥?87.CrossRef
  19.Lakie, M., & Robson, L. G. (1990). Thixotropy in frog single muscle fibres. Experimental Physiology, 75, 123鈥?25.CrossRef
  20.Carey, J. R., & Burghardt, T. P. (1993). Movement dysfunction following central nervous system lesions: A problem of neurologic or muscular impairment? Physical Therapy, 73, 538鈥?47.
  21.Sommerfeld, D. K., Gripenstedt, U., & Welmer, A. K. (2012). Spasticity after stroke: An overview of prevalence, test instruments, and treatments. American Journal of Physical Medicine and Rehabilitation, 91, 814鈥?20.CrossRef
  22.Schindler-Ivens, S., & Shields, R. K. (2000). Low frequency depression of H-reflexes in humans with acute and chronic spinal-cord injury. Experimental Brain Research, 133, 233鈥?41.CrossRef
  23.Misiaszek, J. E. (2003). The H-reflex as a tool in neurophysiology: Its limitations and uses in understanding nervous system function. Muscle and Nerve, 28, 144鈥?60.CrossRef
  24.Cody, F. W., Richardson, H. C., MacDermott, N., & Ferguson, I. T. (1987). Stretch and vibration reflexes of wrist flexor muscles in spasticity. Brain, 110, 433鈥?50.CrossRef
  25.Little, J. W., & Halar, E. M. (1985). H-reflex changes following spinal cord injury. Archives of Physical Medicine and Rehabilitation, 66, 19鈥?2.
  26.Hiersemenzel, L. P., Curt, A., & Dietz, V. (2000). From spinal shock to spasticity: Neuronal adaptations to a spinal cord injury. Neurology, 54, 1574鈥?582.CrossRef
  27.Angel, R. W., & Hofmann, W. W. (1963). The H reflex in normal, spastic, and rigid subjects. Archives of Neurology, 9, 591鈥?96.CrossRef
  28.Yanagisawa, N., Shindo, M., Morita, H., & Yanagawa, S. (1993). Methodological problems in the Hoffmann reflex study of spasticity. Heidelberg: Springer Verlag.CrossRef
  29.Rossi-Durand, C., Jones, K. E., Adams, S., & Bawa, P. (1999). Comparison of the depression of H-reflexes following previous activation in upper and lower limb muscles in human subjects. Experimental Brain Research, 126, 117鈥?27.CrossRef
  30.Fowles, J. R., Sale, D. G., & MacDougall, J. D. (2000). Reduced strength after passive stretch of the human plantarflexors. Journal of Applied Physiology, 89, 1179鈥?188.
  31.Tabary, J. C., Tabary, C., Tardieu, C., Tardieu, G., & Goldspink, G. (1972). Physiological and structural changes in the cat鈥檚 soleus muscle due to immobilization at different lengths by plaster casts. Journal of Physiology London, 224, 231鈥?44.CrossRef
  32.Wu, Y. N., Hwang, M., Ren, Y., Gaebler-Spira, D., & Zhang, L. Q. (2011). Combined passive stretching and active movement rehabilitation of lower-limb impairments in children with cerebral palsy using a portable robot. Neurorehabilitation Neural Repair, 25, 378鈥?85.CrossRef
  33.Waldman, G., Yang, C. Y., Ren, Y., Liu, L., Guo, X., Harvey, R. L., et al. (2013). Effects of robot-guided passive stretching and active movement training of ankle and mobility impairments in stroke. Neurorehabilitation, 32, 625鈥?34.
  34.Chang, Y. J., Fang, C. Y., Hsu, M. J., Lien, H. Y., & Wong, M. K. (2007). Decrease of hypertonia after continuous passive motion treatment in individuals with spinal cord injury. Clinical Rehabilitation, 21, 712鈥?18.CrossRef
  35.Haghighipour, N., Heidarian, S., Shokrgozar, M. A., & Amirizadeh, N. (2012). Differential effects of cyclic uniaxial stretch on human mesenchymal stem cell into skeletal muscle cell. Cell Biology International, 36, 669鈥?75.CrossRef
  36.Barnes, M. P., & Johnson, G. R. (2008). Upper motor neurone syndrome and spasticity : Clinical management and neurophysiology. Cambridge: Cambridge University Press.CrossRef
  37.Phadke, C. P., On, A. Y., Kirazli, Y., Ismail, F., & Boulias, C. (2013). Intrafusal effects of botulinum toxin injections for spasticity: Revisiting a previous paper. Neuroscience Letters, 541, 20鈥?3.CrossRef
  38.Avela, J., Kyrolainen, H., & Komi, P. V. (1999). Altered reflex sensitivity after repeated and prolonged passive muscle stretching. Journal of Applied Physiology, 86, 1283鈥?291.
  39.Garland, S. J. (1991). Role of small diameter afferents in reflex inhibition during human muscle fatigue. Journal of Physiology London, 435, 547鈥?58.CrossRef
  40.Jackson, N. D., Gutierrez, G. M., & Kaminski, T. (2009). The effect of fatigue and habituation on the stretch reflex of the ankle musculature. Journal of Electromyography and Kinesiology, 19, 75鈥?4.CrossRef
  41.Biro, A., Griffin, L., & Cafarelli, E. (2007). Reflex gain of muscle spindle pathways during fatigue. Experimental Brain Research, 177, 157鈥?66.CrossRef
  42.Boudarham, J., Roche, N., Teixeira, M., Hameau, S., Robertson, J., Bensmail, D., & Zory, R. (2014). Relationship between neuromuscular fatigue and spasticity in chronic stroke patients: A pilot study. Journal of Electromyography and Kinesiology, 24, 292鈥?99.CrossRef
  43.Nicol, C., Komi, P. V., Horita, T., Kyrolainen, H., & Takala, T. E. (1996). Reduced stretch-reflex sensitivity after exhausting stretch-shortening cycle exercise. European Journal of Applied Physiology and Occupational Physiology, 72, 401鈥?09.
  44.Gollhofer, A., Komi, P. V., Fujitsuka, N., & Miyashita, M. (1987). Fatigue during stretch-shortening cycle exercises. II. Changes in neuromuscular activation patterns of human skeletal muscle. International Journal of Sports Medicine, 8, 38鈥?7.CrossRef
  45.Shields, R. K., Chang, Y. J., & Ross, M. (1998). Neuromuscular propagation after fatiguing contractions of the paralyzed soleus muscle in humans. Muscle and Nerve, 21, 776鈥?87.CrossRef
  46.Chang, Y. J., & Shields, R. K. (2002). Within-train neuromuscular propagation varies with torque in paralyzed human muscle. Muscle and Nerve, 26, 673鈥?80.CrossRef
  
• 作者单位：Chia-Ying Fang (1) (2)
  Miao-Ju Hsu (3) (4)
  Chih-Chung Chen (1) (5)
  Hsin-Yi Kathy Cheng (6)
  Ching-Chieh Chou (7)
  Ya-Ju Chang (1) (5)
  
  1. Department of Physical Therapy and Graduate Institute of Rehabilitation Science, College of Medicine, Chang Gung University, Taoyuan, 333, Taiwan
  2. Department of Physical Therapy, Tzu Hui Institute of Technology, Pingtung, 367, Taiwan
  3. Department of Physical Therapy, College of Health Science, Kaohsiung Medical University, Kaohsiung, 807, Taiwan
  4. Department of Physical Medicine and Rehabilitation, Kao-hsiung Medical University Hospital, Kaohsiung, 807, Taiwan
  5. Healthy Aging Research Center, Chang Gung University, Taoyuan, 333, Taiwan
  6. Graduate Institute of Early Intervention, College of Medicine, Chang Gung University, Taoyuan, 333, Taiwan
  7. Department of Cell Biology, Emory University School of Medicine, Atlanta, GA, 30322, USA
  
• 刊物类别：Biomedical Engineering; Cell Biology; Imaging / Radiology;
• 刊物主题：Biomedical Engineering; Cell Biology; Imaging / Radiology;
• 出版者：Springer Berlin Heidelberg
• ISSN：2199-4757

文摘

Hypertonia is one of the major causes of movement disorders in individuals with central nervous system lesions. Robot-assisted therapy can minimize the immobilization side-effect such as severe hypertonia by providing repetitive motor practice with minimal labor assistance. The purpose of this study was to design a robot-assisted passive exercise device and establish optimal parameter settings for reducing both reflexive and non-reflexive muscle tone. A custom-made device with a built-in force transducer was developed to provide ankle cyclic passive exercise at various speeds and measure the total resistance during stretching. Ten individuals with spinal cord injury received 8 min of low-speed passive exercise (20 cycles/min), 8 min of high-speed (50 cycles/min) passive exercise, and repeated contractions elicited by electrical stimulation (ES), in randomized order over 3 consecutive weeks. Maximum ES-elicited isometric torque, M waves, H reflexes, and total resistance during stretching were measured before and after each of the treatments. The results show that the H reflex was reduced after passive exercise at both speeds but not after repeated ES-elicited contractions. The reduction of the total resistance during stretching was speed-dependent. Significant fatigue was induced only after repeated ES-elicited contractions. This study successfully developed a robot-assisted passive exercise device, evaluated parameter settings, and provided evidence of the reduction of both reflexive excitability and total muscle tone in hypertonia muscles. Keywords Hypertonia Stretch reflex Spinal cord injury