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High rate of detection of G8P[6] rotavirus in children with acute gastroenteritis in S?o Tomé and Príncipe
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  • 作者:Claudia Istrate ; Sumit Sharma ; Johan Nordgren…
  • 刊名:Archives of Virology
  • 出版年:2015
  • 出版时间:February 2015
  • 年:2015
  • 卷:160
  • 期:2
  • 页码:423-428
  • 全文大小:634 KB
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  • 刊物类别:Biomedical and Life Sciences
  • 刊物主题:Biomedicine
    Virology
    Medical Microbiology
    Infectious Diseases
  • 出版者:Springer Wien
  • ISSN:1432-8798
文摘
The burden of rotavirus infections greatly affects the low-income African countries. In the absence of epidemiological data on pediatric diarrhea in S?o Tomé and Príncipe (STP), a study was conducted from August to December 2011. Rotavirus antigen was detected in 36.7?% of the collected fecal samples (87/237). G8P[6] was identified as the predominant genotype (71.1?% detection rate), while G1P[8] represented only 8.4?%. Phylogenetic analysis of VP7 G8 strains showed clustering within lineage G8d, while VP4 P[6] strains clustered within lineage 1a. Our results represent the first report on rotavirus from STP and show one of the highest detection rates of G8 rotaviruses worldwide.

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