Click inspired synthesis of triazole-linked vanillin glycoconjugates
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- 作者：Pratibha Dwivedi ; Kunj B. Mishra ; Pritika ; Bhuwan B. Mishra…
- 关键词：Vanillin ; Click chemistry ; Carbohydrates ; Glycoconjugates
- 刊名：Glycoconjugate Journal
- 出版年：2017
- 出版时间：February 2017
- 年：2017
- 卷：34
- 期：1
- 页码：61-70
- 全文大小：
- 刊物类别：Biomedical and Life Sciences
- 刊物主题：Biochemistry, general; Pathology;
- 出版者：Springer US
- ISSN：1573-4986
- 卷排序：34
文摘
The 1,3-dipolar cycloaddition of deoxy-azido sugars 1 with alkyne derivatives of p-vanillin, 3-methoxy-4-(prop-2-ynyloxy)benzaldehyde (2) and 2-methoxy-1-(prop-2-ynyloxy)-4-((prop-2-ynyloxy)methyl)benzene) (4) to afford regioselective triazole-linked vanillinglycoconjugates 5 and 6 was investigated in the presence of CuI/DIPEA in dichloromethane. All the developed glycoconjugates were characterized on the basis of IR, NMR, and MS.