Effects of a Terrified-Sound Stress on Serum Proteomic Profiling in Mice

详细信息    查看全文

• 作者：Juan Yang ; Xin Zhang ; Xiaofan Xiong ; Qiuhua Wu…
• 关键词：Terrified ; sound ; induced stress ; Serum proteomic profiling ; Stress release ; Protein expression
• 刊名：Journal of Molecular Neuroscience
• 出版年：2015
• 出版时间：October 2015
• 年：2015
• 卷：57
• 期：2
• 页码：211-218
• 全文大小：996 KB
• 参考文献：Aloe LC, Alleva E, Fiore M (2002) Stress and nerve growth factor finding in animal models and humans. Pharmacol Biochem Behav 73:159-66CrossRef PubMed
  Arrondel C, Vodovar N, Knebelmann B et al (2002) Expression of the nonmuscle myosin heavy chain IIA in the human kidney and screening for MYH9 mutations in Epstein and Fechtner syndromes. J Am Soc Nephrol 13:65-4PubMed
  Biondi M (2001) Chapter. 39: Effects of stress on immune functions: an overview. In Psychoneuroimmunology, 3rd ed, Vol. 2. Academic Press, New York
  Biondi M, Zannino LG (1997) Psychological stress, neuroimmunomodulation, and susceptibility to infectious diseases in animals and man: a review. Psychother Psychosom 66:3-6CrossRef PubMed
  Birkett MA (2011) The Trier Social Stress Test protocol for inducing psychological stress. J Vis Exp 19:32-8
  Carney RM, Freedland KE (2002) Psychological distress as a risk factor for stroke-related mortality. Stroke 33:5-PubMed
  Cashman JR, Zhang J (2006) Human flavin-containing monooxygenases. Annu Rev Pharmacol Toxicol 46:65-00CrossRef PubMed
  Dhabhar FS (2009) Enhancing versus suppressive effects of stress on immune function: implications for immunoprotection and immunopathology. Neuro immunomodulation 16:300-17
  Diamandis EP (2006) Peptidomics for cancer diagnosis: present and future. J Proteome Res 5:2079-082CrossRef PubMed
  Eskandari F, Sternberg EM (2002) Neural-immune interactions in health and disease. Ann N Y Acad Sci 966:20-7CrossRef PubMed
  Geiger M (2007) Protein C inhibitor, a serpin with functions in- and outside vascular biology. Thromb Haemost 97:343-47PubMed
  Giannoglou GD, Koskinas KC (2015) Mental stress and cardiovascular disease: growing evidence into the complex interrelation between mind and heart. Angiology 66:5-CrossRef PubMed
  Hu LL, Yang J, Song TS, Hou N, Liu Y, Zhao XG, Huang C (2014) A new stress model, a scream sound, alters learning and monoamine levels in rat brain. Physiol Behav 123:105-13CrossRef PubMed
  Jones KC, Ballou DP (1986) Reactions of the 4a-hydroperoxide of liver microsomal flavin-containing monooxygenase with nucleophilic and electrophilic substrates. J B C 261:2553-559
  Krueger SK, Williams DE (2005) Mammalian flavin-containing monooxygenases: structure/function, genetic polymorphisms and role in drug metabolism. Pharmacol Ther 106:357-87PubMed Central CrossRef PubMed
  Li BY, Yuan YH, Zhang WQ, He W, Hu J, Chen N (2014) Flavin-containing monooxygenase, a new clue of pathological proteins in the rotenone model of parkinsonism. Neurosci Lett 566:11-6CrossRef PubMed
  Liotta LA, Petricoin EF (2006) Serum peptidome for cancer detection: spinning biological trash into diagnostic gold. J Clin Invest 116:26-0PubMed Central CrossRef PubMed
  Lloyd C, Smith J, Weinger K (2005) Stress and diabetes: a review of the links. Diabetes Spectr 8:121-27CrossRef
  Poulsen LL, Ziegler DM (1995) Multisubstrate flavin-containing monooxygenase: application of mechanism to specificity. Chem–Biol Interact 96:57-3CrossRef PubMed
  Reiche EM, Nunes SO, Morimoto HK (2004) Stress, depression, the immune system, and cancer. Lancet Oncol 5:617-25CrossRef PubMed
  Singh N, Nainani N, Arora P, Venuto RC (2009) CKD in MYH9-related disorders. Am J Kidney Dis 54:732-40CrossRef PubMed
  Vicente-Manzanares M, Ma X, Adelstein RS (2009) Non-muscle myosin II takes centre stage in cell adhesion and migration. Nat Rev Mol Cell Biol 10:778-90PubMed Central CrossRef PubMed
  Wang L, Wang W, Zhao M, Ma L, Li M (2008) Psychological stress induces dysregulation of iron metabolism in rat brain. Neuroscience 155:24-0CrossRef PubMed
  Wei C, Zhou J, Huang X, Li M (2008) Effects of psychological stress on serum iron and erythropoiesis. Int J Hematol 88:52-6CrossRef PubMed
  Yang J, Song YC, Dang CX, Song TS, Liu ZG, Guo YM, Li ZF, Huang C (2012) Serum peptidome profiling in patients with gastric cancer. Clin Exp Med 12:79-7CrossRef PubMed
  Yang J, Hu LL, Song TS, Liu Y, Wu QH, Zhao LY, Liu LY, Zhao XG, Zhang DX, Huang C (2014a) Proteomic changes in female rat hippocampus following exposure to a terrified sound stress. J Mol Neurosci 53:158-65CrossRef PubMed
  Yang J, Hu LL, Wu QH, Liu Y, Zhao LY, Zhao XG, Song TS, Huang C (2014b) A terrified-sound stress induced proteomic changes in adult male rat hippocampus. Physiol Behav 128:32-8CrossRef PubMed
  Yu J, Liu FH, Yin P et al (2011) Integrating miRNA and mRNA expression profiles in response to heat stress-induced injury in rat small intestine. Funct Integr Genomics 11:203-13CrossRef PubMed
  Zhao M, Chen J, Wang W et al (2008) Psychological stress induces hypoferremia through the IL-6-hepcidin axis in rats. BBRC 373:90-3PubMed
  
• 作者单位：Juan Yang (1) (2)
  Xin Zhang (3)
  Xiaofan Xiong (1)
  Qiuhua Wu (1)
  Lingyu Zhao (1)
  Liying Liu (2)
  Yannan Qin (1)
  Tusheng Song (1)
  Chen Huang (1) (2)
  
  1. Department of Cell Biology and Genetics, Basic Medical School, Xi’an Jiaotong University, 76 Western Yanta Road, Xi’an, Shaanxi, 710061, People’s Republic of China
  2. Key Laboratory of Environment and Disease-Related Gene, Ministry of Education, Xi’an Jiaotong University, 76 Western Yanta Road, Xi’an, Shaanxi, 710061, People’s Republic of China
  3. Assisted Reproduction Center, Maternal & Child Health Care Hospital, Xi’an, Shaanxi, 710003, People’s Republic of China
  
• 刊物主题：Neurosciences; Neurochemistry; Cell Biology; Proteomics; Neurology;
• 出版者：Springer US
• ISSN：1559-1166

文摘

The serum proteomic profiles of mice exposed to terrified-sound-induced stress and after stress release were investigated. Serum samples from 32 mice were divided into four groups (n-- each) and analyzed using matrix-assisted laser desorption and ionization time-of-flight mass spectrometry techniques (MALDI-TOF MS) combined with magnetic bead-based weak cation-exchange chromatography. ClinProTools software identified several distinct markers that differed between the stressed and control groups and between the stress released and stressed released controls. Of 33-em class="EmphasisTypeItalic ">m/z peaks that differed among the four groups, 17 were significantly different (P-lt;-.05). Five peaks (m/z: 2793.37, 2924.86, 1979.90, 3492.49, 3880.24) showed significant differences in expression after exposure to terrified-sound stress and returned to control levels after stress release. These were sequence identified as peptide regions of dimethylaniline monooxygenase, myosin-9, uncharacterized protein in Rattus norvegicus, apolipoprotein C-I, and plasma serine protease inhibitor (Serpina 5). Our study provides the first evidence of significant changes in serum proteomic profiles in mice exposed to terrified-sound stress, which suggests that protein expression profiles are affected by the stress. Normal expression levels were restored after stress release, suggesting the activation of self-adjustment mechanisms for the recovery of protein expression levels altered by this stress. Keywords Terrified-sound-induced stress Serum proteomic profiling Stress release Protein expression