Coblation endoscopic lingual lightening (CELL) for obstructive sleep apnea
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  • 作者:Hsueh-Yu Li ; Li-Ang Lee ; Eric J. Kezirian
  • 关键词:Coblation endoscopic lingual lightening ; Tongue base obstruction ; Obstructive sleep apnea ; Uvulopalatopharyngoplasty
  • 刊名:European Archives of Oto-Rhino-Laryngology
  • 出版年:2016
  • 出版时间:January 2016
  • 年:2016
  • 卷:273
  • 期:1
  • 页码:231-236
  • 全文大小:999 KB
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  • 作者单位:Hsueh-Yu Li (1) (2)
    Li-Ang Lee (1)
    Eric J. Kezirian (3)

    1. Department of Otolaryngology, Sleep Center, Linkou-Chang Gung Memorial Hospital, School of Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan
    2. Department of Sleep Medicine, Royal Infirmary Edinburgh, Edinburgh, UK
    3. Department of Otolaryngology-Head and Neck Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
  • 刊物类别:Medicine
  • 刊物主题:Medicine & Public Health
    Otorhinolaryngology
    Neurosurgery
    Head and Neck Surgery
  • 出版者:Springer Berlin / Heidelberg
  • ISSN:1434-4726
文摘
This study investigated the feasibility, safety and efficacy of Coblation endoscopic lingual lightening (CELL) surgery for obstructive sleep apnea (OSA). This study was a retrospective case series in a tertiary referral sleep center. Twenty-five adults with moderate to severe OSA and determined to have retropalatal and tongue base obstruction based on Friedman tongue position III and fiberoptic endoscopy underwent CELL in combination with modified uvulopalatopharyngoplasty, known as relocation pharyngoplasty. CELL involves transoral resection of tongue base muscle tissue and lingual tonsil using Coblation under endoscopic guidance. The mean operation time for CELL was 42.6 ± 13.7 min. Total blood loss for CELL plus relocation pharyngoplasty was <50 ml in all patients. Mean postoperative pain score (sum of total pain scores/sum of total hospitalization day, visual analog scale, 0–10) was 2.6 ± 0.6. Postoperative bleeding and taste disturbance extending beyond 3 months occurred in one patient (4 %) individually. No patients reported tongue weakness or speech dysfunction. Epworth sleepiness scale improved from 9.6 ± 4.9 to 7.5 ± 4.3 (p = 0.023). Apnea–hypopnea index decreased from 45.7 ± 21.7 to 12.8 ± 8.2 events/hour (p < 0.001) 6 months after surgery. The overall response rate was 80 %. CELL is feasible, safe and effective in treating tongue base obstruction in OSA patients who underwent simultaneous relocation pharyngoplasty.

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