Implication of Nrf2/HO-1 pathway in the coloprotective effect of coenzyme Q10 against experimentally induced ulcerative colitis
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- 作者：Ahmed E. Khodir ; Hoda Atef ; Eman Said ; Hassan A. ElKashef…
- 关键词：Ulcerative colitis ; Coenzyme Q10 ; TNF ; α ; Nrf2 ; HO ; 1 ; Caspase ; 3
- 刊名：Inflammopharmacology
- 出版年：2017
- 出版时间：February 2017
- 年：2017
- 卷：25
- 期：1
- 页码：119-135
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- 刊物主题：Pharmacology/Toxicology; Immunology; Rheumatology; Gastroenterology; Dermatology; Allergology;
- 出版者：Springer International Publishing
- ISSN：1568-5608
- 卷排序：25
文摘
PurposeGiven the increased incidence of ulcerative colitis worldwide, the current study was designed to investigate the coloprotective potential of CoQ10 against experimentally induced ulcerative colitis (UC) and specify the implicated mechanisms.