The effect of different collagen modifications for titanium and titanium nitrite surfaces on functions of gingival fibroblasts
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- 作者：U. Ritz ; T. Nusselt ; A. Sewing ; T. Ziebart ; K. Kaufmann…
- 关键词：Titanium ; Titanium nitride ; Collagen ; Surface modification ; RGD ; Gingival fibroblast
- 刊名：Clinical Oral Investigations
- 出版年：2017
- 出版时间：January 2017
- 年：2017
- 卷：21
- 期：1
- 页码：255-265
- 全文大小：
- 刊物类别：Medicine
- 刊物主题：Dentistry;
- 出版者：Springer Berlin Heidelberg
- ISSN：1436-3771
- 卷排序：21
文摘
ObjectivesTargeted modifications of the bulk implant surfaces using bioactive agents provide a promising tool for improvement of the long-term bony and soft tissue integration of dental implants. In this study, we assessed the cellular responses of primary human gingival fibroblasts (HGF) to different surface modifications of titanium (Ti) and titanium nitride (TiN) alloys with type I collagen or cyclic-RGDfK-peptide in order to define a modification improving long-term implants in dental medicine.