A case study of a collision tumor composed of cancers of the bile duct and pancreas

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• 作者：Hideki Izumi ; Daisuke Furukawa ; Naoki Yazawa ; Yoshihito Masuoka…
• 关键词：Collision tumor ; Bile duct cancer ; Pancreatic cancer
• 刊名：Surgical Case Reports
• 出版年：2015
• 出版时间：December 2015
• 年：2015
• 卷：1
• 期：1
• 全文大小：1462KB
• 参考文献：1.Niu G, Jin D, Ji Y, Hou J, Wang D, Lou W. Survival analysis of pancreatic and periampullary collision cancers. J Dig Dis. 2010;11:231鈥?.PubMed
  2.Warren S, Gates O. Multiple primary malignant tumors. A survey of the literature and a statistical study. Am J Cancer. 1932;16:1358鈥?14.
  3.Moertel CG, Dockerty MB, Baggenstoss AH. Multiple primary malignant neoplasms. Cancer. 1961;14:221鈥?0.CrossRef PubMed
  4.Shimizu S, Oshita A, Tashiro H, Amano H, Kobayashi T, Tanaka M, et al. Synchronous double cancers of primary hepatic adenosquamous carcinoma and hepatocellular carcinoma: report of a case. Surg Today. 2013;43:418鈥?3.CrossRef PubMed
  5.Haratake J, Hashimoto H. An immunohistochemical analysis of 13 cases with combined hepatocellular and cholangiocellular carcinoma. Liver. 1995;15:9鈥?5.CrossRef PubMed
  6.Miyaguni T, Muto Y, Kusano T, Yamada M, Matsumoto M, Shiraishi M. Synchronous double cancers of the remnant stomach and pancreas: report of a case. Surg Today. 1995;25:1038鈥?2.CrossRef PubMed
  7.Kamisawa TIT, Egawa N, Tsuruta K, Okamoto A, Kawamura T, Koike M. Study on pancreatic cancer associated with other primary malignancies (in Japan). Suizo (J Jpn Pancr Soc). 1993:164鈥?.
  8.Makino TKY, Takahashi S, Maruyama H, Kohara T, Yokose Y, Emi Y, et al. Clinicopathology of pancreatic cancer analyzed from annual of the pathological autopsy cases in Japan (in Japanese). Tan To Sui (J Gall Pancr). 1984:761鈥?.
  9.Hirono S, Tani M, Terasawa H, Kawai M, Ina S, Uchiyama K, et al. A collision tumor composed of cancers of the bile duct and ampulla of Vater - immunohistochemical analysis of a rare entity of double cancer. Hepatogastroenterology. 2008;55:861鈥?.PubMed
  10.Stukavec J, Jirasek T, Mandys V, Denemark L, Havluj L, Sosna B, et al. Poorly differentiated endocrine carcinoma and intraductal papillary-mucinous neoplasm of the pancreas: description of an unusual case. Pathol Res Pract. 2007;203:879鈥?4.CrossRef PubMed
  11.Eriguchi N, Aoyagi S, Hara M, Okuda K, Tamae T, Fukuda S, et al. Synchronous or metachronous double cancers of the pancreas and other organs: report on 12 cases. Surg Today. 2000;30(8):718鈥?1.CrossRef PubMed
  12.Williams IM, Williams NW, Stock D, Foster ME. Collision tumour of the ampulla of Vater: carcinoid and adenocarcinoma. HPB Surg. 1997;10:241鈥?.CrossRef PubMed Central PubMed
  13.Ferrando Marco J, Pallas Regueira A, Moro Valdezate D, Fern谩ndez Mart铆nez C. Collision tumor of the ampulla of Vater: carcinoid and adenocarcinoma. Rev Esp Enferm Dig. 2007;99:235鈥?.CrossRef PubMed
  
• 作者单位：Hideki Izumi (1)
  Daisuke Furukawa (1)
  Naoki Yazawa (1)
  Yoshihito Masuoka (1)
  Misuzu Yamada (1)
  Kosuke Tobita (1)
  Yohei Kawashima (2)
  Masami Ogawa (2)
  Yoshiaki Kawaguchi (2)
  Kenichi Hirabayashi (3)
  Toshio Nakagohri (1)
  
  1. Department of Gastrointestinal Surgery, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa, 259-1193, Japan
  2. Department of Internal Medicine, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa, 259-1193, Japan
  3. Department of Pathology, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa, 259-1193, Japan
  
• 刊物类别：Surgery;
• 刊物主题：Surgery;
• 出版者：Springer Berlin Heidelberg
• ISSN：2198-7793

文摘

In this case report, we describe the extremely rare case of a collision tumor comprising cancers of the bile duct and the pancreas. A 70-year-old man was referred to our hospital with a diagnosis of obstructive jaundice. He was diagnosed with pancreatic head cancer, and we performed a pancreaticoduodenectomy with lymph node dissection. At laparotomy, there were two palpable masses in the vicinity of the confluence of the cystic duct and the head of the pancreas. The resected specimen demonstrated tumors at the confluence of the cystic duct and in the pancreatic head. Histopathological examination demonstrated a moderately differentiated tubular adenocarcinoma in the pancreatic head and a well-differentiated tubular adenocarcinoma at the confluence of the cystic duct. Immunostaining was negative for p53 and MUC6 in the pancreatic head tumor; however, immunostaining was positive for both in the tumor located at the confluence of the cystic duct. The two tumors were histologically different and were diagnosed as collision cancer caused by the collision of the bile duct and pancreatic cancers. Keywords Collision tumor Bile duct cancer Pancreatic cancer