A Fluorescein-Based Colorimetric and Fluorescent Probe for Hydrazine and its Bioimaging in Live Cells
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- 作者：Gongchun Li ; Yongxiang Liu ; Jianhua Song ; Yong Ye
- 关键词：Fluorescein ; Fluorescence ; Hydrazine
- 刊名：Journal of Fluorescence
- 出版年：2017
- 出版时间：January 2017
- 年：2017
- 卷：27
- 期：1
- 页码：323-329
- 全文大小：
- 刊物类别：Biomedical and Life Sciences
- 刊物主题：Biomedicine, general; Biological and Medical Physics, Biophysics; Biotechnology; Biochemistry, general; Analytical Chemistry;
- 出版者：Springer US
- ISSN：1573-4994
- 卷排序：27
文摘
A turn-on fluorescent probe (FN) for detection of hydrazine has been developed. Probe FN exhibited high selectivity and excellent sensitivity towards hydrazine with a detection limit as low as 4.6 × 10−10 M. Probe FN selectively reacts with hydrazine (N2H4) in a physiological environment, leading to an off-on fluorescence response along with the color change from colorless to yellow, allowing colorimetric detection of hydrazine by the naked eye. Furthermore, probe FN was successfully applied for visualizing hydrazine in living cells.