Protein import complexes in the mitochondrial outer membrane of Amoebozoa representatives

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• 作者：Dorota Buczek ; Małgorzata Wojtkowska ; Yutaka Suzuki ; Seiji Sonobe…
• 关键词：Amoebozoa ; Protein import into mitochondria ; Transcriptome analysis ; TOM complex ; TOB/SAM complex ; ERMES complex
• 刊名：BMC Genomics
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：17
• 期：1
• 全文大小：3,709 KB
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• 作者单位：Dorota Buczek (1) (2)
  Małgorzata Wojtkowska (2)
  Yutaka Suzuki (4)
  Seiji Sonobe (3)
  Yukinori Nishigami (3)
  Monika Antoniewicz (2)
  Hanna Kmita (2)
  Wojciech Makałowski (1)
  
  1. Institute of Bioinformatics, Faculty of Medicine, University of Muenster, Niels Stensen Strasse 14, 48149, Muenster, Germany
  2. Laboratory of Bioenergetics, Institute of Molecular Biology and Biotechnology, Faculty of Biology, Adam Mickiewicz University, Umultowska 89, 61-614, Poznań, Poland
  4. Department of Medical Genome Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba, 277-8562, Japan
  3. Department of Life Science, Graduate School of Life Science, University of Hyogo, Harima Science Park City, Kobe, Hyogo, 678-1297, Japan
  
• 刊物主题：Life Sciences, general; Microarrays; Proteomics; Animal Genetics and Genomics; Microbial Genetics and Genomics; Plant Genetics & Genomics;
• 出版者：BioMed Central
• ISSN：1471-2164

文摘

Background An ancestral trait of eukaryotic cells is the presence of mitochondria as an essential element for function and survival. Proper functioning of mitochondria depends on the import of nearly all proteins that is performed by complexes located in both mitochondrial membranes. The complexes have been proposed to contain subunits formed by proteins common to all eukaryotes and additional subunits regarded as lineage specific. Since Amoebozoa is poorly sampled for the complexes we investigated the outer membrane complexes, namely TOM, TOB/SAM and ERMES complexes, using available genome and transcriptome sequences, including transcriptomes assembled by us.