Maternal use of probiotics during pregnancy and effects on their offspring’s health in an unselected population
详细信息 查看全文
- 作者：Nicole Rutten ; Anne Van der Gugten ; Cuno Uiterwaal…
- 关键词：Probiotics ; Behavioural patterns ; Pregnancy ; Health effects
- 刊名：European Journal of Pediatrics
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：175
- 期：2
- 页码：229-235
- 全文大小：300 KB
- 参考文献：1.Arkkola T, Uusitalo U, Pietikäinen M et al (2006) Dietary intake and use of dietary supplements in relation to demographic variables among pregnant Finnish women. Br J Nutr 96:913–920. doi:10.1017/BJN20061929 CrossRef PubMed
2.Artal R, Catanzaro RB, Gavard JA et al (2007) A lifestyle intervention of weight-gain restriction: diet and exercise in obese women with gestational diabetes mellitus. Appl Physiol Nutr Metab 32:596–601. doi:10.1139/H07-024 CrossRef PubMed
3.Bayrampour H, Heaman M (2011) Comparison of demographic and obstetric characteristics of Canadian primiparous women of advanced maternal age and younger age. J Obstet Gynaecol Can 33:820–829PubMed
4.Bertelsen RJ, Brantsæter AL, Magnus MC, et al. (2013) Probiotic milk consumption in pregnancy and infancy and subsequent childhood allergic diseases. J Allergy Clin Immunol. doi: 10.1016/j.jaci.2013.07.032
5.Berti C, Biesalski HK, Gärtner R et al (2011) Micronutrients in pregnancy: current knowledge and unresolved questions. Clin Nutr 30:689–701. doi:10.1016/j.clnu.2011.08.004 CrossRef PubMed
6.Bödecs T, Horváth B, Szilágyi E et al (2011) Association between health beliefs and health behavior in early pregnancy. Matern Child Health J 15:1316–1323. doi:10.1007/s10995-010-0698-0 CrossRef PubMed
7.Braun LA, Tiralongo E, Wilkinson JM et al (2010) Perceptions, use and attitudes of pharmacy customers on complementary medicines and pharmacy practice. BMC Complement Altern Med 10:38. doi:10.1186/1472-6882-10-38 PubMedCentral CrossRef PubMed
8.Doege K, Grajecki D, Zyriax B-C et al (2012) Impact of maternal supplementation with probiotics during pregnancy on atopic eczema in childhood—a meta-analysis. Br J Nutr 107:1–6. doi:10.1017/S0007114511003400 CrossRef PubMed
9.Enomoto T, Sowa M, Nishimori K et al (2014) Effects of bifidobacterial supplementation to pregnant women and infants in the prevention of allergy development in infants and on fecal microbiota. Allergol Int 63:575–585. doi:10.2332/allergolint.13-OA-0683 CrossRef PubMed
10.Fernández L, Langa S, Martín V et al (2013) The human milk microbiota: origin and potential roles in health and disease. Pharmacol Res 69:1–10. doi:10.1016/j.phrs.2012.09.001 CrossRef PubMed
11.Grobbee DE, Hoes AW, Verheij TJM et al (2005) The Utrecht Health Project: optimization of routine healthcare data for research. Eur J Epidemiol 20:285–287. doi:10.1007/s10654-004-5689-2 CrossRef PubMed
12.Hempel S, Newberry SJ, Maher AR et al (2012) Probiotics for the prevention and treatment of antibiotic-associated diarrhea: a systematic review and meta-analysis. JAMA 307:1959–1969. doi:10.1001/jama.2012.3507 CrossRef PubMed
13.Huurre A, Laitinen K, Rautava S et al (2008) Impact of maternal atopy and probiotic supplementation during pregnancy on infant sensitization: a double-blind placebo-controlled study. Clin Exp Allergy 38:1342–1348. doi:10.1111/j.1365-2222.2008.03008.x CrossRef PubMed
14.Jeurink PV, van Bergenhenegouwen J, Jiménez E et al (2013) Human milk: a source of more life than we imagine. Benef Microbes 4:17–30. doi:10.3920/BM2012.0040 CrossRef PubMed
15.Katier N, Uiterwaall CSPM, De Jong BM et al (2004) The Wheezing Illnesses Study Leidsche Rijn (WHISTLER): rationale and design. Eur J Epidemiol 19:895–903CrossRef PubMed
16.Krzepota J, Putek-Szeląg E (2014) Nutritional habits in the light of general health behaviours of pregnant women. Ann Agric Environ Med 21:425–428. doi:10.5604/1232-1966.1108618 CrossRef PubMed
17.Laitinen K, Collado MC, Isolauri E (2010) Early nutritional environment: focus on health effects of microbiota and probiotics. Benef Microbes 1:383–390. doi:10.3920/BM2010.0045 CrossRef PubMed
18.Laitinen K, Poussa T, Isolauri E (2009) Probiotics and dietary counselling contribute to glucose regulation during and after pregnancy: a randomised controlled trial. Br J Nutr 101:1679–1687. doi:10.1017/S0007114508111461 CrossRef PubMed
19.Luoto R, Laitinen K, Nermes M, Isolauri E (2010) Impact of maternal probiotic-supplemented dietary counselling on pregnancy outcome and prenatal and postnatal growth: a double-blind, placebo-controlled study. Br J Nutr 103:1792–1799. doi:10.1017/S0007114509993898 CrossRef PubMed
20.Molenaar EA, van Ameijden EJC, Vergouwe Y et al (2010) Effect of nutritional counselling and nutritional plus exercise counselling in overweight adults: a randomized trial in multidisciplinary primary care practice. Fam Pract 27:143–150. doi:10.1093/fampra/cmp104 CrossRef PubMed
21.Nauta AJ, Ben Amor K, Knol J et al (2013) Relevance of pre- and postnatal nutrition to development and interplay between the microbiota and metabolic and immune systems. Am J Clin Nutr 98:586S–593S. doi:10.3945/ajcn.112.039644 CrossRef PubMed
22.Niers L, Martín R, Rijkers G et al (2009) The effects of selected probiotic strains on the development of eczema (the PandA study). Allergy 64:1349–1358. doi:10.1111/j.1398-9995.2009.02021.x CrossRef PubMed
23.Perez PF, Doré J, Leclerc M et al (2007) Bacterial imprinting of the neonatal immune system: lessons from maternal cells? Pediatrics 119:e724–e732. doi:10.1542/peds.2006-1649 CrossRef PubMed
24.Rautava S, Kainonen E, Salminen S, Isolauri E (2012) Maternal probiotic supplementation during pregnancy and breast-feeding reduces the risk of eczema in the infant. J Allergy Clin Immunol 130:1355–1360. doi:10.1016/j.jaci.2012.09.003 CrossRef PubMed
25.Sanz Y (2011) Gut microbiota and probiotics in maternal and infant health. Am J Clin Nutr 94:2000S–2005S. doi:10.3945/ajcn.110.001172 CrossRef PubMed
26.Szwajcer EM, Hiddink GJ, Koelen MA, van Woerkum CMJ (2007) Nutrition awareness and pregnancy: implications for the life course perspective. Eur J Obstet Gynecol Reprod Biol 135:58–64. doi:10.1016/j.ejogrb.2006.11.012 CrossRef PubMed
27.Thum C, Cookson AL, Otter DE et al (2012) Can nutritional modulation of maternal intestinal microbiota influence the development of the infant gastrointestinal tract? J Nutr 142:1921–1928. doi:10.3945/jn.112.166231 CrossRef PubMed
28.Van der Gugten AC, Koopman M, Evelein AMV et al (2012) Rapid early weight gain is associated with wheeze and reduced lung function in childhood. Eur Respir J 39:403–410. doi:10.1183/09031936.00188310 CrossRef PubMed
29.Van Putte-Katier N, van der Gugten AC, Uiterwaal CSPM et al (2012) Early life lung function and respiratory outcome in the first year of life. Eur Respir J 40:198–205. doi:10.1183/09031936.00175910 CrossRef PubMed
30.VandeVusse L, Hanson L, Safdar N (2013) Perinatal outcomes of prenatal probiotic and prebiotic administration: an integrative review. J Perinat Neonatal Nurs 27:288–301. doi:10.1097/JPN.0b013e3182a1e15d , quiz E1–2CrossRef PubMed
31.Wehby GL, Castilla EE, Lopez-Camelo JS, Murray JC (2009) Predictors of multivitamin use during pregnancy in Brazil. Int J Public Health 54:78–87. doi:10.1007/s00038-009-8103-8 PubMedCentral CrossRef PubMed
32.Weir Z, Bush J, Robson SC et al (2010) Physical activity in pregnancy: a qualitative study of the beliefs of overweight and obese pregnant women. BMC Pregnancy Childbirth 10:18. doi:10.1186/1471-2393-10-18 PubMedCentral CrossRef PubMed
33.Wulandari LPL, Klinken Whelan A (2011) Beliefs, attitudes and behaviours of pregnant women in Bali. Midwifery 27:867–871. doi:10.1016/j.midw.2010.09.005 CrossRef PubMed - 作者单位：Nicole Rutten (1) (2)
Anne Van der Gugten (1)
Cuno Uiterwaal (3)
Arine Vlieger (2)
Ger Rijkers (4) (5)
Kors Van der Ent (1)
1. Department of Pediatric Pulmonology and Allergology, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Room KH.01.419.0, PO Box 85090, Utrecht, 3508 AB, The Netherlands
2. Department of Pediatrics, St. Antonius Hospital, PO Box 2500, Nieuwegein, 3430 EM, The Netherlands
3. Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, PO Box 85500, Utrecht, 3508 GA, The Netherlands
4. Laboratory of Medical Microbiology and Immunology, St. Antonius Hospital, PO Box 2500, Nieuwegein, 3430 EM, The Netherlands
5. Department of Sciences, University College Roosevelt, PO Box 94, Middelburg, 4330 AB, The Netherlands - 刊物主题：Pediatrics;
- 出版者：Springer Berlin Heidelberg
- ISSN：1432-1076
文摘
Probiotics are used by women in the perinatal period and may improve balance of microbiota, with possible health benefits for both mother and baby. Characteristics and (health) behaviour patterns of mothers using probiotics during pregnancy, and health effects on their offspring, were investigated. Differences between mothers using probiotics during pregnancy and those who did not, were assessed. In total, 341 out of 2491 (13.7 %) mothers reported use of probiotics during pregnancy. There were no significant differences in maternal features (gestation, age, ethnicity, education) between users and non-users. Logistic regression analyses showed that consumption of probiotics was significantly associated with use of homeopathic products [odds ratio (OR) 1.65, 95 % confidence interval (CI) 1.17–2.33, p = 0.005], maternal history of smoking (OR 1.72, 95 % CI 1.25–2.37, p = 0.001) and paternal history of smoking (OR 1.39, 95 % CI 1.01–1.89, p = 0.05). Common disease symptoms during the first year of life in the offspring did not differ between both groups. Conclusion: The use of probiotics or other health-related products without doctor’s prescription during pregnancy might point to compensation for types of less favourable behaviour. Probiotic use during pregnancy does not seem to induce positive health effects in the offspring in an unselected population. What is Known: • Aberrant microbiota compositions have been detected during critical periods when early programming occurs including pregnancy and early neonatal life. • Probiotics modulate intestinal microbiota composition and are associated with positive health effects. What is New: • The use of probiotics or other health-related products without doctor’s prescription during pregnancy is associated with and might point to compensation for types of less favourable behaviour. • Probiotic use during pregnancy does not induce positive health effects in the offspring in this unselected population.