A reliability study using computer-based analysis of finger joint space narrowing in rheumatoid arthritis patients

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• 作者：Katsuya Hatano ; Tamotsu Kamishima ; Kenneth Sutherland…
• 关键词：Rheumatoid arthritis ; Joint space narrowing ; Computer ; based analysis ; Reliability ; Radiography
• 刊名：Rheumatology International
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：37
• 期：2
• 页码：189-195
• 全文大小：
• 刊物主题：Rheumatology;
• 出版者：Springer Berlin Heidelberg
• ISSN：1437-160X
• 卷排序：37

文摘

The joint space difference index (JSDI) is a newly developed radiographic index which can quantitatively assess joint space narrowing progression of rheumatoid arthritis (RA) patients by using an image subtraction method on a computer. The aim of this study was to investigate the reliability of this method by non-experts utilizing RA image evaluation. Four non-experts assessed JSDI for radiographic images of 510 metacarpophalangeal joints from 51 RA patients twice with an interval of more than 2 weeks. Two rheumatologists and one radiologist as well as the four non-experts examined the joints by using the Sharp–van der Heijde Scoring (SHS) method. The radiologist and four non-experts repeated the scoring with an interval of more than 2 weeks. We calculated intra-/inter-observer reliability using the intra-class correlation coefficients (ICC) for JSDI and SHS scoring, respectively. The intra-/inter-observer reliabilities for the computer-based method were almost perfect (inter-observer ICC, 0.966–0.983; intra-observer ICC, 0.954–0.996). Contrary to this, intra-/inter-observer reliability for SHS by experts was moderate to almost perfect (inter-observer ICC, 0.556–0.849; intra-observer ICC, 0.589–0.839). The results suggest that our computer-based method has high reliability to detect finger joint space narrowing progression in RA patients.