Taurine depresses cardiac contractility and enhances systemic heart glucose utilization in the cuttlefish, Sepia officinalis

详细信息    查看全文

• 作者：Tyson J. MacCormack ; N. I. Callaghan ; A. V. Sykes…
• 关键词：Coleoid ; 2 ; Aminoethanesulfonic acid ; Perfused heart ; Branchial heart ; Calcium
• 刊名：Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology
• 出版年：2016
• 出版时间：February 2016
• 年：2016
• 卷：186
• 期：2
• 页码：215-227
• 全文大小：680 KB
• 参考文献：Agnisola C, Houlihan DF (1991) Oxygen supply and in vitro performance of the systemic heart of Octopus vulgaris: effects of haemocyanin. J Exp Biol 157:523–541
  Altimiras J, Hove-Madsen L, Gesser H (1999) Ca2+ uptake in the sarcoplasmic reticulum from the systemic heart of octopod cephalopods. J Exp Biol 202:2531–2537PubMed
  Ballantyne IS, Hochachka PW, Mommsen TP (1981) Studies on the metabolism of the migratory squid, Loligo opalescens: enzymes of tissues and heart mitochondria. Mar Biol Lett 2:75–85
  Bergmeyer HU, Gawehn K, Grassl M (1974) Enzymes as biochemical reagents. In: Bergmeyer HU (ed) Methods of enzymatic analysis, vol 1. Academic Press, New York, pp 425–522
  Bourne GB (1982) Blood pressure in the squid, Loligo pealei. Comp Biochem Physiol 72A:23–27CrossRef
  De la Puerta C, Arrieta FJ, Balsa JA, Botella-Carretero JI, Zamarrón I, Vázquez C (2010) Taurine and glucose metabolism: a review. Nutr Hosp 25:910–919PubMed
  Devlin CL (1993a) An analysis of control of the ventricle of the mollusc Mercenaria mercenaria. I. The ionic basis of autorhythmicity. J Exp Biol 179:47–61
  Devlin CL (1993b) An analysis of control of the ventricle of the mollusc Mercenaria mercenaria. II. Ionic mechanisms involved in excitation by 5-hydroxytryptamine. J Exp Biol 179:63–75
  Dieni CA, Callaghan NI, Gormley PT, Butler KMA, MacCormack TJ (2014) Physiological hepatic response to zinc oxide nanoparticle exposure in the white sucker, Catostomus commersonii. Comp Biochem Physiol 162C:51–61
  Driedzic WR (1985) Contractile performance of cephalopod hearts under anoxic conditions. J Exp Biol 117:471–474
  Driedzic WR, Sidell BD, Stewart JM, Johnston IA (1990) Maximal activities of enzymes of energy metabolism in cephalopod systemic and branchial hearts. Physiol Zool 63:615–629CrossRef
  Foti L, Genoino IT, Agnisola G (1985) In vitro cardiac performance in Octopus vulgaris (Lam). Comp Biochem Physiol 82C:483–488
  Franconi F, Martini F, Stendardi I, Matucci R, Zilletti L, Giotti A (1982) Effect of taurine on calcium levels and contractility in guinea-pig ventricular strips. Biochem Pharmacol 31:3181–3185PubMed CrossRef
  Gesser H, Driedzic WR, Rantin FT, de Freitas JC (1997) Ca2+ regulation of heart contractility in Octopus. J Comp Physiol B 167:474–480CrossRef
  Gutowska MA, Melzner F, Langenbuch M, Bock C, Claireaux G, Pörtner H-O (2010) Acid–base regulatory ability of the cephalopod (Sepia officinalis) in response to environmental hypercapnia. J Comp Physiol B 180:323–335PubMed CrossRef
  Hochachka PW, Mommsen TP, Storey J, Storey KB, Johansen K, French CJ (1983) The relationship between arginine and proline metabolism in cephalopods. Mar Biol Lett 4:1–21
  Hoeger U, Mommsen TP (1985) Role of free amino acids in the oxidative metabolism of cephalopod hearts. In: Gilles R (ed) Circulation, respiration, and metabolism. Current comparative approaches. Springer, Berlin, pp 367–376CrossRef
  Houlihan DF, Agnisola C, Hamilton NM, Genoino IT (1987) Oxygen consumption of the isolated heart of Octopus: effects of power output and hypoxia. J Exp Biol 131:137–157
  Huxtable RJ (1992) Physiological actions of taurine. Physiol Rev 72:101–163PubMed
  Imae M, Asano T, Murakami S (2014) Potential role of taurine in the prevention of diabetes and metabolic syndrome. Amino Acids 46:81–88PubMed CrossRef
  Johansen K, Martin AW (1962) Circulation in the cephalopod, Octopus dofleini. Comp Biochem Physiol 5:161–176PubMed CrossRef
  King AJ, Adamo SA (2006) The ventilatory, cardiac and behavioural responses of resting cuttlefish (Sepia officinalis L.) to sudden visual stimuli. J Exp Biol 209:1101–1111PubMed CrossRef
  Kling G, Schipp R (1987) Comparative ultrastructural and cytochemical analysis of the cephalopod systemic heart and its innervation. Experientia 43:502–511CrossRef
  Lamarre SG, Ditlecadet D, McKenzie DJ, Bonnaud L, Driedzic WR (2012) Mechanisms of protein degradation in mantle muscle and proposed gill remodeling in starved Sepia officinalis. Am J Physiol 303:R427–R437CrossRef
  Lampson WG, Kramer JH, Schaffer SW (1983) Potentiation of the actions of insulin by taurine. Can J Physiol Pharmacol 61:457–463PubMed CrossRef
  Lewbart GA (2006) Invertebrate medicine. Blackwell Publishing, Ames, p 356CrossRef
  Maturo J, Kulakowski EC (1988) Taurine binding to the purified insulin receptor. Biochem Pharmacol 37:3755–3760PubMed CrossRef
  Melzner F, Bock C, Pörtner H-O (2007) Coordination between ventilatory pressure oscillations and venous return in the cephalopod Sepia officinalis under control conditions, spontaneous exercise and recovery. J Comp Physiol B 177:1–17PubMed CrossRef
  Mommsen TP, Hochachka PW (1981) Respiratory and enzymatic properties of squid heart mitochondria. Eur J Biochem 120:345–350PubMed CrossRef
  O’Dor RK, Webber DM (1986) The constraints on cephalopods: why squid aren’t fish. Can J Zool 64:1591–1605CrossRef
  Ott M, Gogvadze V, Orrenius S, Zhivotovsky B (2007) Mitochondria, oxidative stress and cell death. Apoptosis 12:913–922PubMed CrossRef
  Öz E, Erbaş D, Gelir E, Arıcıoğlu A (1999) Taurine and calcium interaction in protection of myocardium exposed to ischemic reperfusion injury. Gen Pharmacol 33:137–141PubMed CrossRef
  Pertseva MN, Shpakov AO, Plesneva SA, Kuznetsova LA (2003) A novel view on the mechanisms of action of insulin and other insulin superfamily peptides: involvement of adenylyl cyclase signaling system. Comp Biochem Physiol 134B:11–36CrossRef
  Robertson JD (1953) Further studies on ionic regulation in marine invertebrates. J Exp Biol 30:277–296
  Satoh H (1994) Cardioprotective actions of taurine against intracellular and extracellular calcium-induced effects. In: Huxtable RJ, Michalk D (eds) Taurine in health and disease. Springer Science + Business Media, New York, pp 181–196CrossRef
  Satoh H, Nakatani T, Tanaka T, Haga S (2002) Cardiac functions and taurine’s actions at different extracellular calcium concentrations in forced swimming stress-loaded rats. Biol Trace Element Res 87:171–182CrossRef
  Schaffer SW, Jong CJ, Ramila KC, Azuma J (2010) Physiological roles of taurine in heart and muscle. J Biomed Sci 17(Suppl 1):S2PubMed PubMedCentral CrossRef
  Schaffer SW, Jong CJ, Ito T, Azuma J (2014) Effect of taurine on ischemia–reperfusion injury. Amino Acids 46:21–30PubMed CrossRef
  Shaffer J, Kocsis J (1981) Taurine mobilizing effects of beta alanine and other inhibitors of taurine transport. Life Sci 28:2727–2736PubMed CrossRef
  Shiels HA, White E (2008) The Frank-Starling mechanism in vertebrate cardiac myocytes. J Exp Biol 211:2005–2013PubMed CrossRef
  Smith PJS (1981) The role of venous pressure in regulation of output from the heart of the octopus, Eledone cirrhosa (Lam.). J Exp Biol 93:243–255
  Storey KB, Storey JM, Johansen K, Hochachka PW (1979) Octopine metabolism in Sepia officinalis: effect of hypoxia and metabolite load on the blood levels of octopine and related compounds. Can J Zool 57:2331–2336CrossRef
  Sykes AV, Domingues PM, Andrade JP (2014) European cuttlefish, Sepia officinalis. In: Iglesias J, Fuentes L, Villanueva R (eds) Cephalopod culture. Springer, Netherlands, pp 175–204CrossRef
  Vislie T (1983) Cell volume regulation in fish heart ventricles with special reference to taurine. Comp Biochem Physiol 76A:507–514CrossRef
  Wells MJ (1979) The heartbeat of Octopus vulgaris. J Exp Biol 78:87–104
  Wells MJ (1980) Nervous control of the heartbeat in Octopus. J Exp Biol 85:111–128PubMed
  Wells MJ, Wells J (1983) The circulatory response to acute hypoxia in Octopus. J Exp Biol 104:59–71
  Zhao X, Jia J, Lin Y (1998) Taurine content in Chinese food and daily taurine intake of Chinese men. In: Schaffer S, Lombardini JB, Huxtable RJ (eds) Taurine 3: cellular and regulatory mechanisms. Springer Science + Business Media, New York, pp 501–505CrossRef
  
• 作者单位：Tyson J. MacCormack (1)
  N. I. Callaghan (1)
  A. V. Sykes (2)
  W. R. Driedzic (3)
  
  1. Department of Chemistry and Biochemistry, Mount Allison University, Sackville, NB, E4L1G8, Canada
  2. C.C.Mar, Centre of Marine Sciences, Universidade do Algarve, Campus de Gambelas, Faro, Portugal
  3. Department of Ocean Sciences, Memorial University of Newfoundland, St. John’s, NL, Canada
  
• 刊物类别：Biomedical and Life Sciences
• 刊物主题：Life Sciences
  Biochemistry
  Biomedicine
  Human Physiology
  Zoology
  Animal Physiology
  
• 出版者：Springer Berlin / Heidelberg
• ISSN：1432-136X

文摘

Taurine is the most abundant amino acid in the blood of the cuttlefish, Sepia officinalis, where levels can exceed 200 mmol L−1. In mammals, intracellular taurine modulates cardiac Ca2+ handling and carbohydrate metabolism at much lower concentrations but it is not clear if it exerts similar actions in cephalopods. Blood Ca2+ levels are high in cephalopods and we hypothesized that taurine would depress cardiac Ca2+ flux and modulate contractility in systemic and branchial hearts of cuttlefish. Heart performance was assessed with an in situ perfused systemic heart preparation and contractility was evaluated using isometrically contracting systemic and branchial heart muscle rings. Stroke volume, cardiac output, and Ca2+ sensitivity were significantly lower in systemic hearts perfused with supplemental taurine (100 mmol L−1) than in controls. In muscle ring preparations, taurine impaired relaxation at high contraction frequencies, an effect abolished by supra-physiological Ca2+ levels. Taurine did not affect oxygen consumption in non-contracting systemic heart muscle, but extracellular glucose utilization was twice that of control preparations. Collectively, our results suggest that extracellular taurine depresses cardiac Ca2+ flux and potentiates glucose utilization in cuttlefish. Variations in taurine levels may represent an important mechanism for regulating cardiovascular function and metabolism in cephalopods. Keywords Coleoid 2-Aminoethanesulfonic acid Perfused heart Branchial heart Calcium