Agonist muscle adaptation accompanied by antagonist muscle atrophy in the hindlimb of mice following stretch-shortening contraction training
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- 作者：Erik P. Rader ; Marshall A. Naimo ; James Ensey…
- 关键词：Stretch ; shortening contractions ; Plantarflexor muscles ; Dorsiflexor muscles ; C57BL6 mice ; Myosin heavy chain ; Muscle physiology ; Biomechanics ; Muscle fiber type
- 刊名：BMC Musculoskeletal Disorders
- 出版年：2017
- 出版时间：December 2017
- 年：2017
- 卷：18
- 期：1
- 全文大小：5482KB
- 刊物主题：Orthopedics; Rehabilitation; Rheumatology; Sports Medicine; Internal Medicine; Epidemiology;
- 出版者：BioMed Central
- ISSN：1471-2474
- 卷排序：18
文摘
BackgroundThe vast majority of dynamometer-based animal models for investigation of the response to chronic muscle contraction exposure has been limited to analysis of isometric, lengthening, or shortening contractions in isolation. An exception to this has been the utilization of a rat model to study stretch-shortening contractions (SSCs), a sequence of consecutive isometric, lengthening, and shortening contractions common during daily activity and resistance-type exercise. However, the availability of diverse genetic strains of rats is limited. Therefore, the purpose of the present study was to develop a dynamometer-based SSC training protocol to induce increased muscle mass and performance in plantarflexor muscles of mice.