Prevention of Contrast-Induced Acute Kidney Injury: an Update
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- 作者：George Chalikias ; Ioannis Drosos ; Dimitrios N. Tziakas
- 关键词：Contrast induced nephropathy ; Acute kidney injury ; Contrast media ; Coronary angiography ; Percutaneous coronary intervention ; Prevention
- 刊名：Cardiovascular Drugs and Therapy
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：30
- 期：5
- 页码：515-524
- 全文大小：364 KB
- 刊物类别：Medicine
- 刊物主题：Medicine & Public Health
Cardiology - 出版者：Springer Netherlands
- ISSN：1573-7241
- 卷排序：30
文摘
Contrast-induced acute kidney injury (CI-AKI) is a common complication of intravascular administration of contrast media used in coronary angiography, percutaneous coronary intervention and other diagnostic and interventional procedures. This review article aims at summarizing the published literature regarding the prevention of CI-AKI, by focusing on available high-quality meta-analyses addressing this matter. Apart from adequate hydration, a number of pharmacologic agents have been proposed as potential candidates to be included in the routine preparation, prior to the patient’s arrival in the cardiac catheterization laboratory. Among them, statins and N-acetylcysteine appear to be the most extensively studied ones. Throughout this article we present the available data on CI-AKI prevention and provide a critical clinical appraisal, as well as a summary of currently available guidelines.