Control and eradication of porcine reproductive and respiratory syndrome virus type 2 using a modified-live type 2 vaccine in combination with a load, close, homogenise model: an area elimination study

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• 作者：Poul H. Rathkjen ; Johannes Dall
• 关键词：Area regional control ; Elimination ; Modified ; live vaccine ; Load close homogenise ; PRRS
• 刊名：Acta Veterinaria Scandinavica
• 出版年：2017
• 出版时间：December 2017
• 年：2017
• 卷：59
• 期：1
• 全文大小：1016KB
• 刊物主题：Veterinary Medicine/Veterinary Science; Animal Anatomy / Morphology / Histology;
• 出版者：BioMed Central
• ISSN：1751-0147
• 卷排序：59

文摘

BackgroundPorcine reproductive and respiratory syndrome virus (PRRSV) causes significant animal and economic losses worldwide. The infection is difficult to control and PRRSV elimination at local level requires coordinated intervention among multiple farms. This case study describes a successful elimination of PRRSV from all 12 herds on the Horne Peninsula, Denmark, using a combination of load, close, homogenise (LCH) using PRRSV type 2 modified-live vaccine, optimised pig flow, and’10 Golden Rules’ (10GR) for biosecurity management. To the authors’ knowledge, this is the first successful European PRRSV area elimination project documented in detail. The PRRSV type 2 modified-live vaccine was used as part of the LCH method in breeding herds. Complete or partial depopulation was performed in some infected herds. A simplified biosecurity protocol (10GR) based on the McREBEL™ system of pig flow management, was employed in all herds and at all times throughout the study.