FabAV antivenin use after copperhead snakebite: clinically indicated or knee-jerk reaction?
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- 作者：Stephen C. Gale ; Jo Ann Peters…
- 关键词：Copperhead ; Venomous snakebite ; Antivenin ; FabAV ; Rural
- 刊名：Journal of Venomous Animals and Toxins including Tropical Diseases
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：22
- 期：1
- 全文大小：431 KB
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Jo Ann Peters (1)
LaDonna Allen (1)
Robert Creath (2)
Viktor Y. Dombrovskiy (3)
1. Division of Trauma, Department of Surgery, East Texas Medical Center, Tyler, TX, USA
4. Director of Trauma Services, East Texas Medical Center, Level 1 Trauma Center, 1020 E. Idel St., Tyler, TX, 75701, USA
2. Department of Emergency Medicine, East Texas Medical Center, Tyler, TX, USA
3. Department of Surgery, Rutgers/RWJMS, New Brunswick, NJ, USA - 刊物主题：Antibodies; Immunology; Infectious Diseases; Tropical Medicine;
- 出版者：BioMed Central
- ISSN：1678-9199
文摘
Background Crotalidae Polyvalent Immune Fab (Ovine) (FabAV) antivenin is commonly recommended after pit viper snakebites. Because copperhead envenomations are usually self-limited, some physicians are reluctant to use this costly treatment routinely, while others follow a more liberal approach. We hypothesized that, in practice, only patients with evidence of significant (moderate or severe) copperhead envenomation [those with snakebite severity score (SSS) > 3] receive FabAV and examined a large cohort to determine the relationship between clinical findings and FabAV administration.