Addressing Knowledge Gaps in the 2013 ACC/AHA Guideline on the Assessment of Cardiovascular Risk: a Review of Recent Coronary Artery Calcium Literature
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- 作者：Vasanth Sathiyakumar ; Roger S. Blumenthal ; Khurram Nasir…
- 关键词：Coronary artery calcium ; Primary prevention ; Cardiovascular disease ; Risk assessment ; Radiation ; Cost ; effectiveness
- 刊名：Current Atherosclerosis Reports
- 出版年：2017
- 出版时间：February 2017
- 年：2017
- 卷：19
- 期：2
- 全文大小：
- 刊物主题：Angiology; Cardiology;
- 出版者：Springer US
- ISSN：1534-6242
- 卷排序：19
文摘
Purpose of ReviewCoronary artery calcium (CAC) has been proposed as an integrator of information from traditionally measured, non-traditionally measured, and unmeasured risk factors for coronary atherosclerosis. The 2013 American College of Cardiology/American Heart Association Guideline on the Assessment of Cardiovascular Risk identified several knowledge gaps regarding CAC, including radiation risks, cost-effectiveness, and improving discrimination and reclassification of estimated risk over the Pooled Cohort Equations in the ACC/AHA Atherosclerotic Cardiovascular Disease Estimator. In this review, we focus on recent CAC literature addressing these knowledge gaps. We further highlight the potential for CAC to enrich future randomized controlled trials.