Atrial Fibrillation Monitoring in Cryptogenic Stroke: the Gaps Between Evidence and Practice
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  • 作者：Krittapoom Akrawinthawong ; Karthik Venkatesh Prasad…
  • 关键词：Cryptogenic stroke ; Atrial fibrillation ; Monitoring ; Review ; Implantable monitors
  • 刊名：Current Cardiology Reports
  • 出版年：2015
  • 出版时间：December 2015
  • 年：2015
  • 卷：17
  • 期：12
  • 全文大小：543 KB
  • 参考文献：1.Britton M, de Faire U, Helmers C, Miah K, Ryding C, Wester PO. Arrhythmias in patients with acute cerebrovascular disease. Acta Med Scand. 1979;205(5):425–8.PubMed
    2.Kishore A, Vail A, Majid A, Dawson J, Lees KR, Tyrrell PJ, et al. Detection of atrial fibrillation after ischemic stroke or transient ischemic attack: a systematic review and meta-analysis. Stroke. 2014;45(2):520–6.CrossRef PubMed
    3.Andrade JG, Field T, Khairy P. Detection of occult atrial fibrillation in patients with embolic stroke of uncertain source: a work in progress. Front Physiol. 2015;6:100.PubMedCentral PubMed
    4.Liao J, Khalid Z, Scallan C, Morillo C, O’Donnell M. Noninvasive cardiac monitoring for detecting paroxysmal atrial fibrillation or flutter after acute ischemic stroke: a systematic review. Stroke. 2007;38(11):2935–40.CrossRef PubMed
    5.Hart RG, Diener HC, Coutts SB, Easton JD, Granger CB, O’Donnell MJ, et al. Embolic strokes of undetermined source: the case for a new clinical construct. Lancet Neurol. 2014;13(4):429–38.CrossRef PubMed
    6.Christensen LM, Krieger DW, Hojberg S, Pedersen OD, Karlsen FM, Jacobsen MD, et al. Paroxysmal atrial fibrillation occurs often in cryptogenic ischaemic stroke. Final results from the SURPRISE study. Eur J Neurol. 2014;21(6):884–9.CrossRef PubMed
    7.Jabaudon D, Sztajzel J, Sievert K, Landis T, Sztajzel R. Usefulness of ambulatory 7-day ECG monitoring for the detection of atrial fibrillation and flutter after acute stroke and transient ischemic attack. Stroke. 2004;35(7):1647–51.CrossRef PubMed
    8.Adams Jr HP, Bendixen BH, Kappelle LJ, Biller J, Love BB, Gordon DL, et al. Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment. Stroke. 1993;24(1):35–41.CrossRef PubMed
    9.Bang OY, Lee PH, Joo SY, Lee JS, Joo IS, Huh K. Frequency and mechanisms of stroke recurrence after cryptogenic stroke. Ann Neurol. 2003;54(2):227–34.CrossRef PubMed
    10.Miller PS, Andersson FL, Kalra L. Are cost benefits of anticoagulation for stroke prevention in atrial fibrillation underestimated? Stroke. 2005;36(2):360–6.CrossRef PubMed
    11.Bang OY, Ovbiagele B, Kim JS. Evaluation of cryptogenic stroke with advanced diagnostic techniques. Stroke. 2014;45(4):1186–94.CrossRef PubMed
    12.Putaala J, Tatlisumak T. Prime time for dissecting the entity of cryptogenic stroke. Stroke. 2014;45(4):950–2.CrossRef PubMed
    13.Suissa L, Lachaud S, Mahagne MH. Optimal timing and duration of continuous electrocardiographic monitoring for detecting atrial fibrillation in stroke patients. J Stroke Cerebrovasc Dis. 2013;22(7):991–5.CrossRef PubMed
    14.Flint AC, Banki NM, Ren X, Rao VA, Go AS. Detection of paroxysmal atrial fibrillation by 30-day event monitoring in cryptogenic ischemic stroke: the Stroke and Monitoring for PAF in Real Time (SMART) Registry. Stroke. 2012;43(10):2788–90.CrossRef PubMed
    15.Bugnicourt JM, Flament M, Guillaumont MP, Chillon JM, Leclercq C, Canaple S, et al. Predictors of newly diagnosed atrial fibrillation in cryptogenic stroke: a cohort study. Eur J Neurol. 2013;20(10):1352–9.CrossRef PubMed
    16.Dussault C, Toeg H, Nathan M, Wang ZJ, Roux JF, Secemsky E. Electrocardiographic monitoring for detecting atrial fibrillation after ischemic stroke or transient ischemic attack: systematic review and meta-analysis. Circ Arrhythm Electrophysiol. 2015;8(2):263–9.CrossRef PubMed
    17.Martin DT, Bersohn MM, Waldo AL, Wathen MS, Choucair WK, Lip GY, et al. Randomized trial of atrial arrhythmia monitoring to guide anticoagulation in patients with implanted defibrillator and cardiac resynchronization devices. Eur Heart J. 2015.
    18.••
Sanna T, Diener HC, Passman RS, Di Lazzaro V, Bernstein RA, Morillo CA, et al. Cryptogenic stroke and underlying atrial fibrillation. N Engl J Med. [Comparative Study Multicenter Study Randomized Controlled Trial Research Support, Non-U.S. Gov’t]. 2014;370(26):2478–86. This study is the first randomized prospective trial to show an increased yield in atrial fibrillation diagnosis with an insertable cardiac monitor.
19.Purerfellner H, Pokushalov E, Sarkar S, Koehler J, Zhou R, Urban L, et al. P-wave evidence as a method for improving algorithm to detect atrial fibrillation in insertable cardiac monitors. Heart Rhythm. 2014;11(9):1575–83.CrossRef PubMed
20.Purerfellner H, Sanders P, Pokushalov E, Di Bacco M, Bergemann T, Dekker LR, et al. Miniaturized Reveal LINQ insertable cardiac monitoring system: first-in-human experience. Heart Rhythm. 2015;12(6):1113–9.CrossRef PubMed
21.•
Gladstone DJ, Spring M, Dorian P, Panzov V, Thorpe KE, Hall J, et al. Atrial fibrillation in patients with cryptogenic stroke. N Engl J Med. [Multicenter Study Randomized Controlled Trial Research Support, Non-U.S. Gov’t]. 2014;370(26):2467–77. This is the largest study to date to show benefits of external monitoring post cryptogenic stroke for diagnosis of atrial fibrillation.
22.Schuchert A, Behrens G, Meinertz T. Impact of long-term ECG recording on the detection of paroxysmal atrial fibrillation in patients after an acute ischemic stroke. Pacing Clin Electrophysiol. 1999;22(7):1082–4.CrossRef PubMed
23.Evans A, Perez I, Yu G, Kalra L. Should stroke subtype influence anticoagulation decisions to prevent recurrence in stroke patients with atrial fibrillation? Stroke. 2001;32(12):2828–32.CrossRef PubMed
24.Kamel H. Heart-rhythm monitoring for evaluation of cryptogenic stroke. N Engl J Med. 2014;370(26):2532–3.CrossRef PubMed
25.Suissa L, Bertora D, Lachaud S, Mahagne MH. Score for the targeting of atrial fibrillation (STAF): a new approach to the detection of atrial fibrillation in the secondary prevention of ischemic stroke. Stroke. 2009;40(8):2866–8.CrossRef PubMed
26.Horstmann S, Rizos T, Guntner J, Hug A, Jenetzky E, Krumsdorf U, et al. Does the STAF score help detect paroxysmal atrial fibrillation in acute stroke patients? Eur J Neurol. 2013;20(1):147–52.CrossRef PubMed
27.Yaghi S, Moon YP, Mora-McLaughlin C, Willey JZ, Cheung K, Di Tullio MR, et al. Left atrial enlargement and stroke recurrence: the northern Manhattan stroke study. Stroke. 2015;46(6):1488–93.CrossRef PubMed
28.Korhonen M, Muuronen A, Arponen O, Mustonen P, Hedman M, Jakala P, et al. Left atrial appendage morphology in patients with suspected cardiogenic stroke without known atrial fibrillation. PLoS ONE. 2015;10(3):e0118822.PubMedCentral CrossRef PubMed
29.Gladstone DJ, Dorian P, Spring M, Panzov V, Mamdani M, Healey JS, et al. Atrial premature beats predict atrial fibrillation in cryptogenic stroke: results from the EMBRACE trial. Stroke. 2015;46(4):936–41.CrossRef PubMed
30.Oppenheimer S. Cerebrogenic cardiac arrhythmias: cortical lateralization and clinical significance. Clin Auton Res. 2006;16(1):6–11.PubMedCentral CrossRef PubMed
31.Gage BF, van Walraven C, Pearce L, Hart RG, Koudstaal PJ, Boode BS, et al. Selecting patients with atrial fibrillation for anticoagulation: stroke risk stratification in patients taking aspirin. Circulation. 2004;110(16):2287–92.CrossRef PubMed
32.January CT, Wann LS, Alpert JS, Calkins H, Cigarroa JE, Cleveland Jr JC, et al. 2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on practice guidelines and the Heart Rhythm Society. Circulation. 2014;130(23):2071–104.CrossRef PubMed
33.Rabinstein AA, Fugate JE, Mandrekar J, Burns JD, Seet RC, Dupont SA, et al. Paroxysmal atrial fibrillation in cryptogenic stroke: a case-control study. J Stroke Cerebrovasc Dis. 2013;22(8):1405–11.CrossRef PubMed
34.•
Glotzer TV, Daoud EG, Wyse DG, Singer DE, Ezekowitz MD, Hilker C, et al. The relationship between daily atrial tachyarrhythmia burden from implantable device diagnostics and stroke risk: the TRENDS study. Circ Arrhythm Electrophysiol. [Multicenter Study Research Support, Non-U.S. Gov’t]. 2009;2(5):474–80. This study investigates the association of AF burden with risk of stroke.
35.•
Boriani G, Glotzer TV, Santini M, West TM, De Melis M, Sepsi M, et al. Device-detected atrial fibrillation and risk for stroke: an analysis of >10,000 patients from the SOS AF project (Stroke prevention Strategies based on Atrial Fibrillation information from implanted devices). Eur Heart J. [Meta-Analysis Research Support, Non-U.S. Gov’t]. 2014;35(8):508–16. This large study showed that AF burden is associated with stroke risk.
36.Healey JS, Connolly SJ, Gold MR, Israel CW, Van Gelder IC, Capucci A, et al. Subclinical atrial fibrillation and the risk of stroke. N Engl J Med. 2012;366(2):120–9.CrossRef PubMed
37.Glotzer TV, Hellkamp AS, Zimmerman J, Sweeney MO, Yee R, Marinchak R, et al. Atrial high rate episodes detected by pacemaker diagnostics predict death and stroke: report of the Atrial Diagnostics Ancillary Study of the MOde Selection Trial (MOST). Circulation. 2003;107(12):1614–9.CrossRef PubMed
38.McCarthy L. ACP Journal Club: ambulatory ECG monitoring for 30 d increased AF detection more than 24 h of ECG monitoring after cryptogenic stroke. Ann Intern Med. 2014;161(10):JC2.CrossRef PubMed
39.Kernan WN, Ovbiagele B, Black HR, Bravata DM, Chimowitz MI, Ezekowitz MD, et al. Guidelines for the prevention of stroke in patients with stroke and transient ischemic attack: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2014;45(7):2160–236.CrossRef PubMed
40.Arsava EM, Bas DF, Atalar E, Has AC, Oguz KK, Topcuoglu MA. Ischemic stroke phenotype in patients with nonsustained atrial fibrillation. Stroke. 2015;46(3):634–40.CrossRef PubMed
41.Botto GL, Padeletti L, Santini M, Capucci A, Gulizia M, Zolezzi F, et al. Presence and duration of atrial fibrillation detected by continuous monitoring: crucial implications for the risk of thromboembolic events. J Cardiovasc Electrophysiol. 2009;20(3):241–8.CrossRef PubMed
42.Kamel H, Hegde M, Johnson DR, Gage BF, Johnston SC. Cost-effectiveness of outpatient cardiac monitoring to detect atrial fibrillation after ischemic stroke. Stroke. 2010;41(7):1514–20.CrossRef PubMed
  • 作者单位：Krittapoom Akrawinthawong (1)
    Karthik Venkatesh Prasad (1)
    Ali Akbar Mehdirad (1)
    Scott Wayne Ferreira (1)

    1. Electrophysiology Division, The Center for Comprehensive Cardiovascular Care, St. Louis University Hospital and School of Medicine, 3635 Vista Avenue, Desloge Tower (13th Floor), St. Louis, MO, 63110, USA
  • 刊物主题：Cardiology;
  • 出版者：Springer US
  • ISSN：1534-3170
    • 文摘
    Identifying occult paroxysmal atrial fibrillation as the etiology of cryptogenic stroke has been a top research priority in the past decade. This is because prompt initiation of anticoagulation has significantly decreased subsequent stroke risk. Available evidence suggests that prolonged cardiac monitoring after stroke increases the likelihood of detecting atrial fibrillation. However, further research is required to fill in the gaps in regard to the optimal period of monitoring, candidates for monitoring, etc. Here, we review the current evidence supporting the use of prolonged monitoring for cryptogenic stroke patients and discuss the directions of future research.

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