Circulating tumor microemboli (CTM) and vimentin+ circulating tumor cells (CTCs) detected by a size-based platform predict worse prognosis in advanced colorectal cancer patients during chemotherapy
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- 作者：Dejun Zhang ; Lei Zhao ; Pengfei Zhou ; Hong Ma ; Fang Huang…
- 关键词：Circulating tumor cells ; Circulating tumor microemboli ; Colorectal cancer ; Survival ; Vimentin
- 刊名：Cancer Cell International
- 出版年：2017
- 出版时间：December 2017
- 年：2017
- 卷：17
- 期：1
- 全文大小：5748KB
- 刊物主题：Cancer Research; Cell Biology;
- 出版者：BioMed Central
- ISSN：1475-2867
- 卷排序：17
文摘
BackgroundCirculating tumor cells (CTCs) detected in peripheral blood (PB) of cancer patients can be identified as isolated CTCs and circulating tumor microemboli (CTM). This study aimed to evaluate the prognostic value of CTM detection and CTC phenotype in advanced colorectal cancer (CRC) patients during chemotherapy.