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1. Department of Surgery II, Tokyo Women’s Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo, 162-8666, Japan
ISSN:1436-2813
文摘
Purpose The aim of this study was to examine the risk factors for and to evaluate strategies for preventing pouchitis as a postoperative complication of ulcerative colitis (UC). Methods A total of 119 cases of UC in which restorative proctocolectomy with an ileal pouch-anal anastomosis (IPAA) was performed at our institution between 2000 and 2012 was investigated; nine patients in whom it was impossible to close the ileostomy due to an intractable anal fistula or pelvic abscess were excluded. Results The cumulative risk of developing pouchitis 5?years after IPAA with stoma closure was 31.0?%. Significant relationships with pouchitis were found for the surgical indication (p?=?0.0126) and surgical method (p?=?0.0214). A significant correlation was found between pouchitis and cuffitis. Pouchitis was significantly more common in the cases with cuffitis than in those without (p?=?0.0002). There was also a significantly different cumulative incidence observed between the cases with and without cuffitis (p?p?=?0.2730). Conclusion The cumulative incidence rate of pouchitis was 10.6?% at 1?year, 15.1?% at 2?years and 31.0?% at 5?years. Controlling cuffitis is important to prevent pouchitis.