Influence of vaginal lactoferrin administration on amniotic fluid cytokines and its role against inflammatory complications of pregnancy
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- 作者：Martina Maritati ; Manola Comar ; Nunzia Zanotta ; Silva Seraceni…
- 关键词：Amniotic fluid ; Lactoferrin ; Pregnancy ; Mediators ; Cytokines ; Inflammatory complications ; Abortion ; Amniocentesis
- 刊名：Journal of Inflammation
- 出版年：2017
- 出版时间：December 2017
- 年：2017
- 卷：14
- 期：1
- 全文大小：600KB
- 刊物主题：Immunology; Allergology; Cytokines and Growth Factors; Rheumatology; Pharmacology/Toxicology; Gastroenterology;
- 出版者：BioMed Central
- ISSN：1476-9255
- 卷排序：14
文摘
BackgroundAn altered amniotic cytokine profile has been reported in inflammatory pregnancy complications with a leading role for IL-6, a marker of the foetal systemic inflammatory response. Up to this date there is no exhaustive information neither on the foetal cytokine balance nor on the best method for its modulation. We aimed to evaluate the influence of vaginal lactoferrin administration on amniotic fluid concentration of 47 cytokines, chemokines and growth factors.