Initial experience in Japan with HeartWare ventricular assist system

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• 作者：Hiroyuki Nishi (1)
  Koichi Toda (1)
  Shigeru Miyagawa (1)
  Yasushi Yoshikawa (1)
  Satsuki Fukushima (1)
  Shunsuke Saito (1)
  Daisuke Yoshioka (1)
  Tetsuya Saito (1)
  Takayoshi Ueno (1)
  Taichi Sakaguchi (1)
  Yoshiki Sawa (1)
  
• 关键词：Ventricular assist device ; Heart failure ; Surgery
• 刊名：Journal of Artificial Organs
• 出版年：2014
• 出版时间：June 2014
• 年：2014
• 卷：17
• 期：2
• 页码：149-156
• 全文大小：
• 参考文献：1. Frazier OH, Rose EA, Oz MC, Dembitsky W, McCarthy P, Radovancevic B, Poirier VL, Dasse KA, HeartMate LVAS. Investigators. Left Ventricular Assist System. Multicenter clinical evaluation of the HeartMate vented electric left ventricular assist system in patients awaiting heart transplantation. J Thorac Cardiovasc Surg. 2001;122:1186-5. CrossRef
  2. Rose EA, Gelijns AC, Moskowitz AJ, Heitjan DF, Stevenson LW, Dembitsky W, Long JW, Ascheim DD, Tierney AR, Levitan RG, Watson JT, Meier P, Ronan NS, Shapiro PA, Lazar RM, Miller LW, Gupta L, Frazier OH, Desvigne-Nickens P, Oz MC, Poirier VL. Randomized evaluation of mechanical assistance for the treatment of congestive heart failure (REMATCH) Study Group. Long-term use of a left ventricular assist device for end-stage heart failure. N Engl J Med. 2001;15:1435-3. CrossRef
  3. Aaronson KD, Slaughter MS, Miller LW, McGee EC, Cotts WG, Acker MA, Jessup ML, Gregoric ID, Loyalka P, Frazier OH, Jeevanandam V, Anderson AS, Kormos RL, Teuteberg JJ, Levy WC, Naftel DC, Bittman RM, Pagani FD, Hathaway DR, Boyce SW. HeartWare ventricular assist device (HVAD) Bridge to transplant ADVANCE trial investigators. Use of an intrapericardial, continuous-flow, centrifugal pump in patients awaiting heart transplantation. Circulation. 2012;125:3191-00. CrossRef
  4. Saito S, Matsumiya G, Sakaguchi T, Miyagawa S, Yoshikawa Y, Yamauchi T, Kuratani T, Sawa Y. Risk factor analysis of long-term support with left ventricular assist system. Circ J. 2010;74:715-2. CrossRef
  5. Saito S, Matsumiya G, Sakaguchi T, Fujita T, Kuratani T, Ichikawa H, Sawa Y. Fifteen-year experience with Toyobo paracorporeal left ventricular assist system. J Artif Organs. 2009;12:27-4. CrossRef
  6. Kurihara C, Ono M, Nishimura T, Saito A, Taketani T, Hisagi M, Nawata K, Kinoshita O, Morota T, Motomura N, Kyo S. Use of DuraHeart^? support for more than 1?year as the first successful bridge to heart transplantation in Japan. J Artif Organs. 2011;14:67-. CrossRef
  7. Yamazaki K, Kihara S, Akimoto T, Tagusari O, Kawai A, Umezu M, Tomioka J, Kormos RL, Griffith BP, Kurosawa H. EVAHEART: an implantable centrifugal blood pump for long-term circulatory support. Jpn J Thorac Cardiovasc Surg. 2002;50:461-. CrossRef
  8. Frazier OH, Myers TJ, Gregoric ID, Khan T, Delgado R, Croitoru M, Miller K, Jarvik R, Westaby S. Initial clinical experience with the Jarvik 2000 implantable axial-flow left ventricular assist system. Circulation. 2002;105:2855-0. CrossRef
  9. Strueber M, O’Driscoll G, Jansz P, Khaghani A, Levy WC, Wieselthaler GM. HeartWare investigators. Multicenter evaluation of an intrapericardial left ventricular assist system. J Am Coll Cardiol. 2011;57:1375-2. CrossRef
  10. Wieselthaler GM, O’Driscoll G, Jansz P, Khaghani A, Strueber M. HVAD clinical investigators. Initial clinical experience with a novel left ventricular assist device with a magnetically levitated rotor in a multi-institutional trial. J Heart Lung Transplant. 2010;29:1218-5. CrossRef
  11. Popov AF, Hosseini MT, Zych B, Mohite P, Hards R, Krueger H, Bahrami T, Amrani M, Simon AR. Clinical experience with HeartWare left ventricular assist device in patients with end-stage heart failure. Ann Thorac Surg. 2012;93:810-. CrossRef
  12. Dell’aquila AM, Schneider SR, Schlarb D, Redwan B, Sindermann JR, Ellger B, Stypmann J, Tjan TD, Scheld HH, Hoffmeier A. Initial clinical experience with the HeartWare left ventricular assist system: a single-center report. Ann Thorac Surg. 2013;95:170-. CrossRef
  13. Yoshioka D, Sakaguchi T, Saito S, Miyagawa S, Nishi H, Yoshikawa Y, Fukushima S, Ueno T, Kuratani T, Sawa Y. Initial experience of conversion of Toyobo paracorporeal left ventricular assist device to DuraHeart left ventricular assist device. Circ J. 2012;76:372-. CrossRef
  14. Takatani S, Matsuda H, Hanatani A, Nojiri C, Yamazaki K, Motomura T, Ohuchi K, Sakamoto T, Yamane T. Mechanical circulatory support devices (MCSD) in Japan: current status and future directions. J Artif Organs. 2005;8:13-7. CrossRef
  15. Meyer AL, Malehsa D, Bara C, Budde U, Slaughter MS, Haverich A, Strueber M. Acquired von Willebrand syndrome in patients with an axial flow left ventricular assist device. Circ Heart Fail. 2010;3:675-1. CrossRef
  16. Uriel N, Pak SW, Jorde UP, Jude B, Susen S, Vincentelli A, Ennezat PV, Cappleman S, Naka Y, Mancini D. Acquired von Willebrand syndrome after continuous-flow mechanical device support contributes to a high prevalence of bleeding during long-term support and at the time of transplantation. J Am Coll Cardiol. 2010;56:1207-3. CrossRef
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• 作者单位：Hiroyuki Nishi (1)
  Koichi Toda (1)
  Shigeru Miyagawa (1)
  Yasushi Yoshikawa (1)
  Satsuki Fukushima (1)
  Shunsuke Saito (1)
  Daisuke Yoshioka (1)
  Tetsuya Saito (1)
  Takayoshi Ueno (1)
  Taichi Sakaguchi (1)
  Yoshiki Sawa (1)
  
  1. Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, 2-2 Yamada-Oka, Suita, Osaka, 565-0871, Japan
  
• ISSN：1619-0904

文摘

We describe the first clinical experiences in Japan with the HeartWare ventricular assist device (HVAD: HeartWare Inc., Miami Lakes, FL, USA) in patients awaiting heart transplantation. Nine patients (6 males, 3 females; mean 33.5?±?7.8?years; New York Heart Association class III or IV) received the HVAD as a bridge to transplantation between 2011 and 2012. Six had dilated cardiomyopathy, 2 secondary cardiomyopathy, and 1 dilated phase hypertrophic cardiomyopathy. All operations were uneventful, with a mean operation time of 269?±?77?min and cardiopulmonary bypass time of 121?±?40?min. One required a temporary right ventricular assist device and was weaned on postoperative day 20, while another required pump exchange due to foreign tissue in the inflow. Mean support duration was 245?±?162?days (range: 50-35?days) and mean pump blood flow at 1?month postoperatively was 4.8?±?0.8?l/min. There was no mortality after 30?days, though 1 patient died during support due to cerebral hemorrhage. Presently, the others are waiting for heart transplantation without problems, except 1 who suffered from an active infection. There was no pump mechanical failure in any case. The HeartWare pump enables quick implantation with acceptable morbidity and mortality. Our preliminary results indicate that this left ventricular assist device is safe for circulatory assistance for heart transplant candidates in Japan.