Xenogeneic acellular dermal matrix in combination with pectoralis major myocutaneous flap reconstructs hypopharynx and cervical esophagus

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• 作者：Danhui Yin ; Qinglai Tang ; Shuang Wang…
• 关键词：Xenogeneic ADM ; Pectoralis major myocutaneous flap ; Hypopharyngeal carcinoma ; Cervical esophagus
• 刊名：European Archives of Oto-Rhino-Laryngology
• 出版年：2015
• 出版时间：November 2015
• 年：2015
• 卷：272
• 期：11
• 页码：3457-3461
• 全文大小：922 KB
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• 作者单位：Danhui Yin (1)
  Qinglai Tang (1)
  Shuang Wang (1)
  Shisheng Li (1)
  Xiangbo He (1)
  Jiajia Liu (1)
  Bingbing Liu (1)
  Mi Yang (1)
  Xinming Yang (1)
  
  1. Department of Otolaryngology Head and Neck Surgery, The Second Xiangya Hospital, Central South University, Changsha, 410011, Hunan, People’s Republic of China
  
• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Otorhinolaryngology
  Neurosurgery
  Head and Neck Surgery
  
• 出版者：Springer Berlin / Heidelberg
• ISSN：1434-4726

文摘

The aim of this study was to explore xenogeneic acellular dermal matrix (ADM) in combination with pectoralis major myocutaneous flap in hypopharynx and cervical esophagus reconstruction. A total of five patients were treated with this surgical method to reconstruct hypopharynx and cervical esophagus in Second Xiangya Hospital between January 2012 and April 2013. Four of them had hypopharyngeal carcinoma with laryngeal and cervical esophageal invasion, while the fifth patient with hypopharyngeal cancer had developed scars and atresia after postoperative radiotherapy. The defect length after hypopharyngeal and cervical esophageal resection was 6- cm, and was repaired by a combination of ADM and pectoralis major myocutaneous flap by our team. Interestingly, the four patients had primary healing and regained their eating function about 2- weeks after surgery, the fifth individual suffered from pharyngeal fistula, but recovered after dressing change about 2 months. Postoperative esophageal barium meals revealed that the pharynx and esophagus were unobstructed in all five patients. Xenogeneic ADM in combination with pectoralis major myocutaneous flap for hypopharynx and cervical esophagus reconstruction is a simple, safe and effective method with fewer complications. Nevertheless, according to the defect length of the cervical esophagus, the patients need to strictly follow the medical advice. Keywords Xenogeneic ADM Pectoralis major myocutaneous flap Hypopharyngeal carcinoma Cervical esophagus