Unbiased estimates of cerebrospinal fluid β-amyloid 1–42 cutoffs in a large memory clinic population

详细信息    查看全文

• 作者：Daniela Bertens ; Betty M. Tijms ; Philip Scheltens…
• 关键词：Alzheimer’s disease ; MCI ; Cerebrospinal fluid ; Diagnosis
• 刊名：Alzheimer's Research & Therapy
• 出版年：2017
• 出版时间：December 2017
• 年：2017
• 卷：9
• 期：1
• 全文大小：1029KB
• 刊物主题：Neurosciences; Neurology; Geriatrics/Gerontology; Geriatric Psychiatry;
• 出版者：BioMed Central
• ISSN：1758-9193
• 卷排序：9

文摘

BackgroundWe sought to define a cutoff for β-amyloid 1–42 in cerebrospinal fluid (CSF), a key marker for Alzheimer’s disease (AD), with data-driven Gaussian mixture modeling in a memory clinic population.