Daxx and TCF4 interaction links to oral squamous cell carcinoma growth by promoting cell cycle progression via induction of cyclin D1 expression
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- 作者：Gu-Jiun Lin ; Yen-Sung Huang ; Chih-Kung Lin ; Shing-Hwa Huang…
- 关键词：OSCC ; Daxx ; TCF4 ; Cyclin D1 ; Cell cycle
- 刊名：Clinical Oral Investigations
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：20
- 期：3
- 页码：533-540
- 全文大小：572 KB
- 刊物类别：Medicine
- 刊物主题：Dentistry
- 出版者：Springer Berlin / Heidelberg
- ISSN：1436-3771
文摘
Objectives Death domain-associated protein (Daxx) has been recently implicated as a positive factor in ovarian cancer and prostate cancer, but the role of Daxx in oral squamous cell carcinoma (OSCC) has never been addressed. Herein, we investigate the expression and function of Daxx in OSCC.