Association of maternal diabetes/glycosuria and pre-pregnancy body mass index with offspring indicators of non-alcoholic fatty liver disease
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- 作者：Sumaiya Patel ; Debbie A. Lawlor ; Mark Callaway ; Corrie Macdonald-Wallis…
- 关键词：Pregnancy diabetes ; Glycosuria ; Obesity ; NAFLD ; Fetal overnutrition ; ALSPAC
- 刊名：BMC Pediatrics
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：16
- 期：1
- 全文大小：788 KB
- 刊物主题：Pediatrics; Internal Medicine;
- 出版者：BioMed Central
- ISSN：1471-2431
文摘
Background Little is known about early life determinants of non-alcoholic fatty liver disease (NAFLD). We examined associations of maternal pregnancy diabetes/glycosuria and pre-pregnancy body mass index (BMI) with offspring markers of NAFLD and liver pathology and examined mediation by birthweight and concurrent offspring adiposity.