Decidualization of uterine adenomyoma in a pregnant woman: a case report with immunohistochemical study

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• 作者：Tadashi Terada
• 关键词：Uterus ; Pregnancy ; Adenomyoma ; Decidualization ; Immunohistopathology
• 刊名：Archives of Gynecology and Obstetrics
• 出版年：2015
• 出版时间：February 2015
• 年：2015
• 卷：291
• 期：2
• 页码：399-402
• 全文大小：1,421 KB
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• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Gynecology
  Obstetrics and Perinatology
  Endocrinology
  Human Genetics
  
• 出版者：Springer Berlin / Heidelberg
• ISSN：1432-0711

文摘

Background Decidualization of uterine adenomyoma has not been reported, to the best of the author’s knowledge. Aim To report a case of uterine adenomyoma with decidualization. Case report A 43-year-old pregnant woman with “myoma-underwent cesarean operation and “myomectomy-at 37 gestation weeks. The operation was successful, and the baby and mother were healthy. Grossly, the “myoma-measured 12?×?10?×?10?cm, and the consistency was firm. Microscopically, the tumor was adenomyoma consisting of smooth muscle bundles and endometrial islands. Characteristically, the endometrial stroma showed marked decidualization. An immunohistochemical study showed that the decidual cells were positive for pancytokeratin AE1/3, pancytokeratin CAM5.2, cytokeratin (CK)7, CK18, vimentin, CA125, CD10, estrogen receptor (ER), progesterone receptor (PgR), and Ki-67 (labeling 1?%). They were negative for CK34βE12, CK5/6, CK8, CK14, CK19, CK20, EMA, p63, desmin, α-smooth muscle actin, S100 protein, CK34, CD68, and p53. These results show that marked decidualization occurs in adenomyoma during pregnancy, and that the decidual cells are positive for pancytokeratin AE1/3, pancytokeratin CAM5.2, CK7, CK18, vimentin, CA125, CD10, ER, and PgR. Conclusion A rare case of uterine adenomyoma with decidualization is reported.