Lead exposure and early child neurodevelopment among children 12–24 months in Kinshasa, the Democratic Republic of Congo

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• 作者：Espérance Kashala-Abotnes ; Pépé Penghele Mumbere…
• 关键词：Childhood ; Lead exposure ; Neurodevelopment ; Temperament ; Kinshasa/DRC
• 刊名：European Child & Adolescent Psychiatry
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：25
• 期：12
• 页码：1361-1367
• 全文大小：418 KB
• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Psychiatry
  
• 出版者：Springer Berlin / Heidelberg
• ISSN：1435-165X
• 卷排序：25

文摘

Childhood lead exposure remains a problem in developing countries, and little is known about its effects on early child neurodevelopment and temperament in the Democratic Republic of Congo (DRC). We, therefore, conducted this study to determine the association between lead exposure and the neurodevelopment and behaviour of children aged 12–24 months in Kinshasa, DRC. A cross-sectional study was conducted between February and June 2012, and parents of 104 children were invited to participate. Blood lead levels (BLLs) of each child were tested using the flame atomic spectrophotometry method. All children were subject to a clinical examination and assessed with two selected early child neurodevelopmental tools, the Gensini–Gavito and the baby characteristics questionnaire, to measure their neurodevelopment and temperament. Detectable BLLs ranged from 1 to 30 μg/dl with a geometric mean of 6.9 (SD 4.8) μg/dl. BLLs at 5–9 and ≥10 μg/dl were significantly associated with the child temperament (p <0.05). Perinatal and maternal factors did not seem to affect early child neurodevelopment and temperament. Children exposed to lead were reported with more temperament difficulties at even blood lead levels <10 μg/dl, suggesting the need for preventive and intervention measures to reduce lead exposure among children in Kinshasa, DRC.