Blood serum concentration of lipids and lipoproteins and body composition

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• 作者：A. I. Kozlov (12)
  G. G. Vershubskaya (12)
  E. D. Sanina (23)
  Yu. A. Ateeva (1)
  N. N. Potolitsyna (4)
  A. M. Kaneva (4)
  O. V. Rogachevskaya (5)
  E. R. Boiko (4)
• 关键词：apolipoprotein E &#8211 ; cholesterol &#8211 ; triglycerides &#8211 ; lipoproteins &#8211 ; body mass index &#8211 ; body surface area &#8211 ; body muscle &#8211 ; body fat
• 刊名：Human Physiology
• 出版年：2012
• 出版时间：May 2012
• 年：2012
• 卷：38
• 期：3
• 页码：324-330
• 全文大小：163.0 KB
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• 作者单位：1. Perm State National Pedagogical University, Perm, 614990 Russia2. Institute of Developmental Physiology, Russian Academy of Education, Moscow, 119121 Russia3. Vavilov Institute of General Genetics, Russian Academy of Science, Moscow, 119991 Russia4. Institute of Physiology, Ural Branch, Russian Academy of Sciences, Syktyvkar, 167982 Russia5. Komi State Pedagogical Institute, Syktyvkar, 167982 Russia
• 刊物类别：Biomedical and Life Sciences
• 刊物主题：Life Sciences
  Life Sciences
  Human Physiology
  Biomedicine
  Russian Library of Science
  
• 出版者：MAIK Nauka/Interperiodica distributed exclusively by Springer Science+Business Media LLC.
• ISSN：1608-3164

文摘

The goal of this study was to analyze the relationship of the blood serum apolipoprotein E (apoE), total cholesterol (TC), triglycerides (TG), and high- and low-density lipoproteins (HDLP, LDLP) levels with the body mass index (BMI), relative body surface area (RBSA), and the body muscle (BM) and body fat (BF) amounts. The study was carried out in male and female subjects aged 14&#8211;16 years (adolescent age group 1: n ₁M = 141, n ₁F = 151) and 18&#8211;25 years (young adult group 2: n ₂M = 141, n ₂F =46). No significant correlations of serum TG and HDL with the somatometric indices were found. The T-lated with the fat component (r ₁ = 0.164; r ₂ = 0.418) and negatively, with the muscle component of body composition (r ₁ = −0.165; r ₂ = −0.352) in female subject samples. Blood serum apoE is significantly correlated with body composition (r ₁ = −0.168 for BF; r ₁ = 0.266, p < 0.05 for BM) in female adolescent subjects. These correlations are significant (p < 0.06) in male subjects aged 14&#8211;16 years. The TC and LDLP contents are negatively correlated with RBSA (r ₂ = −0.386 and −0.377, respectively) and positively correlated with BMI (r ₂ = 0.413 and 0.415, respectively; p < 0.05) in young adult female subjects. With age, correlations between the fat content and apoE concentration change in female subject samples. The content of apoE decreases with increasing BF in female subjects aged 14&#8211;15 years; the correlation disappears in the age interval from 16 to 17 years. An increase in BF is accompanied by an increase in the apoE concentration in female subjects aged 18&#8211;19 years and older.