Analysis of Blood Trace Elements and Biochemical Indexes Levels in Severe Craniocerebral Trauma Adults with Glasgow Coma Scale and Injury Severity Score

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• 作者：Guangtao Xu (1) (2)
  Bo Hu (3)
  Guiqian Chen (2)
  Xiaojun Yu (1)
  Jianming Luo (1)
  Junyao Lv (1)
  Jiang Gu (1)
  
  1. National Key Disciplines ; Department of Forensic and Pathology ; Shantou University Medical College ; 515041 ; Shantou ; Guangdong Province ; People鈥檚 Republic of China
  2. Department of Forensic and Pathology ; Jiaxing University Medical College ; 314001 ; Jiaxing ; Zhejiang Province ; People鈥檚 Republic of China
  3. Department of Pathology ; Jiaxing Hospital of Traditional Chinese Medicine ; 314001 ; Jiaxing ; Zhejiang Province ; People鈥檚 Republic of China
  
• 关键词：Trace element ; Trauma ; Craniocerebral injury ; Injury severity score
• 刊名：Biological Trace Element Research
• 出版年：2015
• 出版时间：April 2015
• 年：2015
• 卷：164
• 期：2
• 页码：192-197
• 全文大小：1,000 KB
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• 刊物主题：Biochemistry, general; Biotechnology; Nutrition; Oncology;
• 出版者：Springer US
• ISSN：1559-0720

文摘

We aimed to investigate the correlation between the Glasgow Coma Scale (GCS), the injury severity score (ISS) and serum levels of trace elements (TE) in severe trauma patients to analyze alteration of the levels of trace elements and serum biochemical indexes in the period of admission from 126 adult cases of severe brain trauma with traffic accidents. Multi-trace elements for patients in the trauma-TE groups were used. The results indicated that all patients presented an acute trace elements deficiency syndrome (ATEDs) after severe trauma, and the correlation between ISS and serum levels of Fe, Zn, and Mg was significant. Compared to the normal control group, levels of the trace elements in serum were significantly decreased after trauma, suggesting that enhancement of immunity to infection and multiple organ failure (MOF) via the monitoring and supplement of trace elements will be a good strategy to severe traumatic patients in clinics.