参考文献:1. Lelkes, E., B.R. Unsworth, and P.I. Lelkes. 2001. Reactive oxygen species, apoptosis and altered NGF-induced signaling in PC12 pheochromocytoma cells cultured in elevated glucose: an / in vitro cellular model for diabetic neuropathy. / Neurotox Res 3: 189鈥?03. CrossRef 2. Negi, G., A. Kumar, and S.S. Sharma. 2011. Nrf2 and NF-kappaB modulation by sulforaphane counteracts multiple manifestations of diabetic neuropathy in rats and high glucose-induced changes. / Curr Neurovasc Res 8: 294鈥?04. CrossRef 3. Imrie, H., A. Abbas, and M. Kearney. 2010. Insulin resistance, lipotoxicity and endothelial dysfunction. / Biochim Biophys Acta 1801: 320鈥?26. CrossRef 4. Savary, S., D. Trompier, P. Andreoletti, F. Le Borgne, J. Demarquoy, and G. Lizard. 2012. Fatty acids-induced lipotoxicity and inflammation. / Curr Drug Metab 13: 1358鈥?0. CrossRef 5. Diakogiannaki, E., H.J. Welters, and N.G. Morgan. 2008. Differential regulation of the endoplasmic reticulum stress response in pancreatic beta-cells exposed to long-chain saturated and monounsaturated fatty acids. / J Endocrinol 197: 553鈥?63. CrossRef 6. Sabin, M.A., C.E. Stewart, E.C. Crowne, S.J. Turner, L.P. Hunt, G.I. Welsh, M.J. Grohmann, J.M. Holly, and J.P. Shield. 2007. Fatty acid-induced defects in insulin signalling, in myotubes derived from children, are related to ceramide production from palmitate rather than the accumulation of intramyocellular lipid. / J Cell Physiol 211: 244鈥?52. CrossRef 7. Unger, R. H. 1995. Lipotoxicity in the pathogenesis of obesity-dependent NIDDM. Genetic and clinical implications. Diabetes 44: 863鈥?70 8. Boden, G., X. Chen, J. Ruiz, J.V. White, and L. Rossetti. 1994. Mechanisms of fatty acid-induced inhibition of glucose uptake. / J Clin Invest 93: 2438鈥?446. CrossRef 9. Smith, A.G., and J.R. Singleton. 2012. Diabetic neuropathy. / Continuum (Minneap Minn) 18: 60鈥?4. 10. Vincent, A.M., J.M. Hayes, L.L. McLean, A. Vivekanandan-Giri, S. Pennathur, and E.L. Feldman. 2009. Dyslipidemia-induced neuropathy in mice: the role of oxLDL/LOX-1. / Diabetes 58: 2376鈥?385. CrossRef 11. Xu, H., B. Wu, F. Jiang, S. Xiong, B. Zhang, G. Li, S. Liu, Y. Gao, C. Xu, G. Tu, H. Peng, S. Liang, and H. Xiong. 2013. High fatty acids modulate P2X(7) expression and IL-6 release / via the p38 MAPK pathway in PC12 cells. / Brain Res Bull 94: 63鈥?0. CrossRef 12. Loddick, S.A., A.V. Turnbull, and N.J. Rothwell. 1998. Cerebral interleukin-6 is neuroprotective during permanent focal cerebral ischemia in the rat. / J Cereb Blood Flow Metab 18: 176鈥?79. CrossRef 13. Klein, M.A., J.C. Moller, L.L. Jones, H. Bluethmann, G.W. Kreutzberg, and G. Raivich. 1997. Impaired neuroglial activation in interleukin-6 deficient mice. / Glia 19: 227鈥?33. CrossRef 14. Nakamachi, T., M. Tsuchida, N. Kagami, S. Yofu, Y. Wada, M. Hori, D. Tsuchikawa, A. Yoshikawa, N. Imai, K. Nakamura, S. Arata, and S. Shioda. 2012. IL-6 and PACAP receptor expression and localization after global brain ischemia in mice. / J Mol Neurosci 48: 518鈥?25. CrossRef 15. Murphy, P.G., J. Grondin, M. Altares, and P.M. Richardson. 1995. Induction of interleukin-6 in axotomized sensory neurons. / J Neurosci 15: 5130鈥?138. 16. Song, D.K., Y.B. Im, J.S. Jung, H.W. Suh, S.O. Huh, J.H. Song, and Y.H. Kim. 1999. Central injection of nicotine increases hepatic and splenic interleukin 6 (IL-6) mRNA expression and plasma IL-6 levels in mice: involvement of the peripheral sympathetic nervous system. / FASEB J 13: 1259鈥?267. 17. Orellana, D.I., R.A. Quintanilla, C. Gonzalez-Billault, and R.B. Maccioni. 2005. Role of the JAKs/STATs pathway in the intracellular calcium changes induced by interleukin-6 in hippocampal neurons. / Neurotox Res 8: 295鈥?04. CrossRef 18. Campbell, I.L., C.R. Abraham, E. Masliah, P. Kemper, J.D. Inglis, M.B. Oldstone, and L. Mucke. 1993. Neurologic disease induced in transgenic mice by cerebral overexpression of interleukin 6. / Proc Natl Acad Sci U S A 90: 10061鈥?0065. CrossRef 19. Nelson, T.E., E.A. Olde, R. Hernandez, A. Puro, S. Huitron-Resendiz, C. Hao, P.N. De Graan, and D.L. Gruol. 2012. Altered synaptic transmission in the hippocampus of transgenic mice with enhanced central nervous systems expression of interleukin-6. / Brain Behav Immun 26: 959鈥?71. CrossRef 20. Zhu, J., X.F. Bai, E. Mix, and H. Link. 1997. Cytokine dichotomy in peripheral nervous system influences the outcome of experimental allergic neuritis: dynamics of mRNA expression for IL-1 beta, IL-6, IL-10, IL-12, TNF-alpha, TNF-beta, and cytolysin. / Clin Immunol Immunopathol 84: 85鈥?4. CrossRef 21. Sugiyama, T. 2014. Role of P2X7 receptors in the development of diabetic retinopathy. / World J Diabetes 5: 141鈥?45. 22. Alves, L.A., R.J. Bezerra, R.X. Faria, L.G. Ferreira, and S.F.V. Da. 2013. Physiological roles and potential therapeutic applications of the P2X7 receptor in inflammation and pain. / Molecules 18: 10953鈥?0972. CrossRef 23. Lister, M.F., J. Sharkey, D.A. Sawatzky, J.P. Hodgkiss, D.J. Davidson, A.G. Rossi, and K. Finlayson. 2007. The role of the purinergic P2X7 receptor in inflammation. / J Inflamm (Lond) 4: 5. CrossRef 24. Di Virgilio, F., D. Ferrari, and E. Adinolfi. 2009. P2X(7): a growth-promoting receptor鈥攊mplications for cancer. / Purinergic Signal 5: 251鈥?56. CrossRef 25. Adinolfi, E., M.G. Callegari, D. Ferrari, C. Bolognesi, M. Minelli, M.R. Wieckowski, P. Pinton, R. Rizzuto, and F. Di Virgilio. 2005. Basal activation of the P2X7 ATP receptor elevates mitochondrial calcium and potential, increases cellular ATP levels, and promotes serum-independent growth. / Mol Biol Cell 16: 3260鈥?272. CrossRef 26. Volonte, C., S. Apolloni, S.D. Skaper, and G. Burnstock. 2012. P2X7 receptors: channels, pores and more. / CNS Neurol Disord Drug Targets 11: 705鈥?21. CrossRef 27. Solini, A., P. Chiozzi, A. Morelli, E. Adinolfi, R. Rizzo, O.R. Baricordi, and F. Di Virgilio. 2004. Enhanced P2X7 activity in human fibroblasts from diabetic patients: a possible pathogenetic mechanism for vascular damage in diabetes. / Arterioscler Thromb Vasc Biol 24: 1240鈥?245. CrossRef 28. Solini, A., P. Chiozzi, S. Falzoni, A. Morelli, R. Fellin, and F. Di Virgilio. 2000. High glucose modulates P2X7 receptor-mediated function in human primary fibroblasts. / Diabetologia 43: 1248鈥?256. CrossRef 29. Vonend, O., C.M. Turner, C.M. Chan, A. Loesch, G.C. Dell鈥橝nna, K.S. Srai, G. Burnstock, and R.J. Unwin. 2004. Glomerular expression of the ATP-sensitive P2X receptor in diabetic and hypertensive rat models. / Kidney Int 66: 157鈥?66. CrossRef 30. Zhang, F., H. Wang, Q. Wu, Y. Lu, J. Nie, X. Xie, and J. Shi. 2013. Resveratrol protects cortical neurons against microglia-mediated neuroinflammation. / Phytother Res 27(3): 344鈥?49. CrossRef 31. Sun, A.Y., Q. Wang, A. Simonyi, and G.Y. Sun. 2010. Resveratrol as a therapeutic agent for neurodegenerative diseases. / Mol Neurobiol 41: 375鈥?83. CrossRef 32. Orsu, P., B.V. Murthy, and A. Akula. 2013. Cerebroprotective potential of resveratrol through anti-oxidant and anti-inflammatory mechanisms in rats. / J Neural Transm 120: 1217鈥?3. CrossRef 33. Li, F., Q. Gong, H. Dong, and J. Shi. 2012. Resveratrol, a neuroprotective supplement for Alzheimer鈥檚 disease. / Curr Pharm Des 18: 27鈥?3. CrossRef 34. Frozza, R.L., Bernardi, A., Hoppe, J.B., Meneghetti, A.B.., Battastini, A.M., Pohlmann, A.R., Guterres, S.S., and Salbego, C. 2013. Lipid-core nanocapsules improve the effects of resveratrol against Abeta-induced neuroinflammation. / J Biomed Nanotechnol 9: 2086鈥?104. CrossRef 35. Hirose, H., Y.H. Lee, L.R. Inman, Y. Nagasawa, J.H. Johnson, and R.H. Unger. 1996. Defective fatty acid-mediated beta-cell compensation in Zucker diabetic fatty rats. Pathogenic implications for obesity-dependent diabetes. / J Biol Chem 271: 5633鈥?637. CrossRef 36. Tang, Y., and G.D. Li. 2004. Chronic exposure to high glucose impairs bradykinin-stimulated nitric oxide production by interfering with the phospholipase-C-implicated signalling pathway in endothelial cells: evidence for the involvement of protein kinase C. / Diabetologia 47: 2093鈥?104. CrossRef 37. Livak, K.J., and T.D. Schmittgen. 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 2(鈭扗elta Delta C(T)) Method. / Methods 25: 402鈥?08. CrossRef 38. Naim, M., S. Bhat, K.N. Rankin, S. Dennis, S.F. Chowdhury, I. Siddiqi, P. Drabik, T. Sulea, C.I. Bayly, A. Jakalian, and E.O. Purisima. 2007. Solvated interaction energy (SIE) for scoring protein-ligand binding affinities. 1. Exploring the parameter space. / J Chem Inf Model 47: 122鈥?33. CrossRef 39. Chang, L., and M. Karin. 2001. Mammalian MAP kinase signalling cascades. / Nature 410: 37鈥?0. CrossRef 40. Siddiqui, M.A., Kashyap, M.P., Kumar, V., Al-Khedhairy, A.A., Musarrat, J., and Pant, A.B.. 2010. Protective potential of trans-resveratrol against 4-hydroxynonenal induced damage in PC12 cells. / Toxicol In Vitro 24: 1592鈥?598. CrossRef 41. North, R.A. 2002. Molecular physiology of P2X receptors. / Physiol Rev 82(4): 1013鈥?067. 42. Zhou, H., Q. Chen, D.L. Kong, J. Guo, Q. Wang, and S.Y. Yu. 2011. Effect of resveratrol on gliotransmitter levels and p38 activities in cultured astrocytes. / Neurochem Res 36: 17鈥?6. CrossRef 43. Han, Y., Jiang, C., Tang, J., Wang, C., Wu, P., Zhang, G., Liu, W., Jamangulova, N., Wu, X., and Song, X. 2014. Resveratrol reduces morphine tolerance by inhibiting microglial activation / via AMPK signalling. Eur J Pain [Epub ahead of print] 44. Armstrong, J.N., T.B. Brust, R.G. Lewis, and B.A. MacVicar. 2002. Activation of presynaptic P2X7-like receptors depresses mossy fiber-CA3 synaptic transmission through p38 mitogen-activated protein kinase. / J Neurosci 22: 5938鈥?945. 45. Friedle, S.A., V.M. Brautigam, M. Nikodemova, M.L. Wright, and J.J. Watters. 2011. The P2X7-Egr pathway regulates nucleotide-dependent inflammatory gene expression in microglia. / Glia 59: 1鈥?3. CrossRef 46. Oliver, M.F., and L.H. Opie. 1994. Effects of glucose and fatty acids on myocardial ischaemia and arrhythmias. / Lancet 343: 155鈥?58. CrossRef 47. Ando, R.D., and B. Sperlagh. 2013. The role of glutamate release mediated by extrasynaptic P2X7 receptors in animal models of neuropathic pain. / Brain Res Bull 93: 80鈥?5. CrossRef
刊物类别:Medicine
刊物主题:Medicine & Public Health Rheumatology Internal Medicine Pharmacology and Toxicology Pathology