Neuropsychological Status of Heroin Users Undergoing Methadone Maintenance in Harm Reduction Program and Therapeutic Community
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- 作者：J. Oliveira ; P. Lopes ; P. Gamito ; H. Trigo…
- 关键词：Harm reduction ; Therapeutic community ; Methadone maintenance ; Cognition ; Heroin
- 刊名：International Journal of Mental Health and Addiction
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：14
- 期：2
- 页码：141-148
- 全文大小：301 KB
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P. Lopes (1) (2) (3)
P. Gamito (1) (2)
H. Trigo (3) (4)
P. Sargento (2)
B. Rosa (1) (2)
R. Coutinho (3) (5)
1. COPELABS / EPCV, University Lusófona, Campo Grande, 376., 1749-024, Lisbon, Portugal
2. School of Psychology and of Life Sciences, University Lusófona, Lisbon, Portugal
3. Ares do Pinhal, Lisbon, Portugal
4. ET Santarém, ARS Lisboa e Vale do Tejo, Santarém, Portugal
5. ET Xabregas, ARS Lisboa e Vale do Tejo, Lisbon, Portugal - 刊物主题：Public Health; Health Psychology; Psychology, general; Rehabilitation; Psychiatry; Community and Environmental Psychology;
- 出版者：Springer US
- ISSN：1557-1882
文摘
The neuropsychological consequences of opioid abuse are particularly evident in attention, memory and executive functioning, but it remains unclear whether these consequences persist in heroin users doing methadone in harm reduction programs and therapeutic community treatments. Thus, the current study aimed to assess these cognitive domains in distinct clinical groups of heroin users undergoing methadone maintenance. The sample consisted of 110 participants divided in four groups (low threshold methadone program, short-term community treatment, long-term community treatment, drug-free controls). These groups were compared regarding memory and attentional abilities. Multiple linear regressions were then conducted to obtain standardized effect sizes for significant comparisons. Results showed a better attentional and memory function in patients that were in opioid dependence treatment in community opposed to patients in harm reduction programs (p’s < 0.05). Standardized effect sizes suggest larger improvements in cognition in long-term heroin-abstinent individuals doing methadone maintenance. These results highlight the detrimental effect of heroin use in cognitive function, but also suggest that this decrement may be reversed during long-term opioid dependence treatment.