Sudden cardiac death in CKD patients

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• 作者：Beata Franczyk-Skóra ; Anna Gluba-Brzózka…
• 关键词：Sudden cardiac death ; Chronic kidney disease ; Risk factors ; Treatment
• 刊名：International Urology and Nephrology
• 出版年：2015
• 出版时间：June 2015
• 年：2015
• 卷：47
• 期：6
• 页码：971-982
• 全文大小：613 KB
• 参考文献：1.Kannel WB, Wilson PW, D’Agostino RB, Cobb J (1998) Sudden coronary death in women. Am Heart J 136(2):205-12PubMed
  2.Pun PH, Lehrich RW, Smith SR, Middleton JP (2007) Predictors of survival after cardiac arrest in outpatient hemodialysis clinics. Clin J Am Soc Nephrol 2:491-00PubMed
  3.US renal data system: annual data report, national institutes of health, national institute of diabetes and digestive and kidney diseases, 2005
  4.Henry RM, Kostense PJ, Bos G, Dekker JM, Nijpels G, Heine RJ, Bouter LM, Stehouwer CD (2002) Mild renal insufficiency is associated with increased cardiovascular mortality: the Hoorn Study. Kidney Int 62:1402-407PubMed
  5.USRDS annual data report, Bethesda, national institutes of health, national institute of diabetes and digestive and kidney diseases, 2014
  6.Atlas of chronic kidney disease and end-stage renal disease in the United States, national institutes of health, national institute of diabetes and digestive and kidney diseases. U.S. renal data system, USRDS 2012 annual data report
  7.Pun PH, Middleton JP (2012) Sudden cardiac death in hemodialysis patients: a comprehensive care approach to reduce risk. Blood Purif 33:183-89PubMed
  8.USRDS annual data report. Bethesda, National institutes of health, national institute of diabetes and digestive and kidney diseases, 2006
  9.U.S. renal data system: USRDS 2013 annual data report. Bethesda, MD: National institutes of health, national institute of diabetes and digestive and kidney diseases
  10.U.S. renal data system: USRDS 2012 annual data report. Bethesda, MD: National institutes of health, national institute of diabetes and digestive and kidney diseases
  11.USRDS annual data report. Bethesda, national institutes of health, national institute of diabetes and digestive and kidney diseases, 2010
  12.Lehrich RW, Pun PH, Tanenbaum ND, Smith SR, Middleton JP (2007) Automated external defibrillators and survival from cardiac arrest in the outpatient hemodialysis clinic. J Am Soc Nephrol 18:312-20PubMed
  13.Bleyer AJ, Hartman J, Brannon PC, Reeves-Daniel A, Satko SG, Russell G (2006) Characteristics of sudden death in hemodialysis patients. Kidney Int 69:2268-273PubMed
  14.Zipes DP, Wellens HJJ (1998) Clinical cardiology: new frontiers. Sudden cardiac death. Circulation 98:2334-351PubMed
  15.Jouven X, Desnos M, Guerot C, Ducimetière P (1999) Predicting sudden death in the population: the Paris Prospective Study I. Circulation 99(15):1978-983PubMed
  16.Albert CM, Ruskin JN (2001) Risk stratifiers for sudden cardiac death (SCD) in the community: primary prevention of SCD. Cardiovasc Res 50(2):186-96PubMed
  17.Guidelines Committee (2003) 2003 European Society of Hypertension–European Society of Cardiology guidelines for the management of arterial hypertension. J Hypertens 21:1011-053
  18.Tin LL, Beevers DG, Lip GY (2002) Hypertension, left ventricular hypertrophy, and sudden death. Curr Cardiol Rep 4(6):449-57PubMed
  19.Saadeh AM, Jones JV (2001) Predictors of sudden cardiac death in never previously treated patients with essential hypertension: long-term follow-up. J Hum Hypertens 15(10):677-80PubMed
  20.Kannel WB, Gordon T, Castelli WP, Margolis JR (1970) Electrocardiographic left ventricular hypertrophy and risk of coronary heart disease. The Framingham study. Ann Intern Med 72(6):813-22PubMed
  21.Meier P, Vogt P, Blanc E (2001) Ventricular arrhythmias and sudden cardiac death in end-stage renal disease patients on chronic hemodialysis. Nephron 87:199-14PubMed
  22.Qing DP, Ding H, Vadgama J, Wu YY, Kopple JD (1999) Elevated myocardial cytosolic calcium impairs insulin-like growth factor-1-stimulated protein synthesis in chronic renal failure. J Am Soc Nephrol 10:84-2PubMed
  23.Wase A, Basit A, Nazir R, Jamal A, Shah S, Khan T, Mohiuddin I, White C, Saklayen M, McCullough PA (2004) Impact of chronic kidney disease upon survival among implantable cardioverter–defibrillator recipients. J Interv Card Electrophysiol 11:199-04PubMed
  24.Saravanan P, Davidson NC (2010) Risk Assessment for sudden cardiac death in dialysis patients. Circ Arrhythm Electrophysiol 3:553-59PubMed
  25.Mark PB, Johnston N, Groenning BA, Foster JE, Blyth KG, Martin TN, Steedman T, Dargie HJ, Jardine AG (2006) Redefinition of uremic cardiomyopathy by contrast-enhanced cardiac magnetic resonance imaging. Kidney Int 69:1839-845PubMed
  26.Schietinger BJ, Brammer GM, Wang H, Christopher JM, Kwon KW, Mangrum AJ, Mangrum JM, Kramer CM (2008) Patterns of late gadolinium enhancement in chronic hemodialysis patients. JACC Cardiovasc Imaging 1:450-56PubMed Central PubMed
  27.Burton JO, Jefferies HJ, Selby NM, McIntyre CW (2009) Hemodialysis-induced cardiac injury: determinants and associated outcomes. Clin J Am Soc Nephrol 4:914-20PubMed Central PubMed
  28.Amann K, Breitbach M, Ritz E, Mall G (1998) Myocyte/capillary mismatch in the heart of uremic patients. J Am Soc Nephrol 9:1018-022
• 作者单位：Beata Franczyk-Skóra (1)
  Anna Gluba-Brzózka (1) (4)
  Jerzy Krzysztof Wranicz (2)
  Maciej Banach (3) (4)
  Robert Olszewski (5)
  Jacek Rysz (1) (4)
  
  1. Department of Nephrology, Hypertension and Family Medicine, WAM University Hospital, ?eromskiego 113, 90-549, Lodz, Poland
  4. Healthy Aging Research Center, Medical University of Lodz, Lodz, Poland
  2. Chair of Cardiology and Cardiac Surgery, Department of Electrocardiology, WAM University Hospital, Lodz, Poland
  3. Department of Nephrology, Medical University of Lodz, Lodz, Poland
  5. Department of Cardiology and Internal Medicine, Military Medical Institute, Warsaw, Poland
  
• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Nephrology
  Urology and Andrology
  
• 出版者：Springer Netherlands
• ISSN：1573-2584

文摘

The risk of sudden cardiac death (SCD) is high in chronic kidney disease patients, and it increases with the progression of kidney function deterioration. The most common causes of SDC are the following: ventricular tachycardia, ventricular tachyarrhythmia, tachycardia torsade de pointes, sustained ventricular fibrillation and bradyarrhythmia. Dialysis influences cardiovascular system and results in hemodynamic disturbances as well as electrolyte shifts altering myocardial electrophysiology. Studies suggest that this procedure exerts both detrimental (poor volume control can exacerbate hypertension and left ventricle hypertrophy) and beneficial effects (associated with fluid removal and subsequent decrease in left ventricle stretch). Dialysis-related vulnerability to serious arrhythmias is the result of sudden shifts in fluid status and electrolytes, particularly potassium, which alter the physiological milieu. Also Ca2+ ions, in which concentration alters during dialysis, are of key importance in the contraction of vascular smooth muscle cells and cardiac myocytes, thus exerting significant effects on hemodynamics. Due to the fact that SCD occurs with similar frequency in peritoneal dialysis and in hemodialysis patients, it seems that end-stage renal disease factors are more important than the specific ones associated with dialysis type. The results of randomized trials suggested that hemodialysis patients may not derive the same benefit of cardiovascular disease therapy including beta-blockers, calcium channel blockers and angiotensin-converting enzyme inhibitors as the general population with normal kidney function. Noninvasive tests used to stratify SCD risk in HD patients have poor positive value, and thus, combining tests including HRV, baroreceptor sensitivity and effectiveness index as well as its function indices and heart rate turbulence should be implemented. There are only few large randomized placebo-controlled trials assessing the influence of cardioprotective medications or implantable cardioverter defibrillator (ICD) implantation in dialysis patients on life quality and survival, and their results are sometimes contradictory. The decision concerning treatment and/or ICD implantation in this group of patients should be made on the basis of careful assessment of individual risk factors. Moreover, due to the high hazard of cardiovascular mortality including SCD in dialysis patients, physicians should concentrate on the early selection of high-risk patients, monitoring them and introduction of preventive measures.