World Kidney Day 2016: Averting the legacy of kidney disease—focus on childhood
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  • 作者:Julie R. Ingelfinger ; Kamyar Kalantar-Zadeh ; Franz Schaefer
  • 关键词:Chronic kidney disease ; Pediatrics ; Congenital anomalies of the kidney and urinary tract (CAKUT) ; Developmental origins of health and disease (DoHAD)
  • 刊名:Pediatric Nephrology
  • 出版年:2016
  • 出版时间:March 2016
  • 年:2016
  • 卷:31
  • 期:3
  • 页码:343-348
  • 全文大小:371 KB
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  • 作者单位:Julie R. Ingelfinger (1)
    Kamyar Kalantar-Zadeh (1)
    Franz Schaefer (1)
    on behalf of the World Kidney Day Steering Committee (1)

    1. International Society of Nephrology, In Collaboration with International Federation of Kidney Foundation, Rues de Fabriques 1B, 1000, Brussels, Belgium
  • 刊物类别:Medicine
  • 刊物主题:Medicine & Public Health
    Pediatrics
  • 出版者:Springer Berlin / Heidelberg
  • ISSN:1432-198X
文摘
World Kidney Day 2016 focuses on kidney disease in childhood and the antecedents of adult kidney disease that can begin in earliest childhood. Chronic kidney disease (CKD) in childhood differs from that in adults, as the largest diagnostic group among children includes congenital anomalies and inherited disorders, with glomerulopathies and kidney disease in the setting of diabetes being relatively uncommon. In addition, many children with acute kidney injury will ultimately develop sequelae that may lead to hypertension and CKD in later childhood or in adult life. Children born early, or who are small-for-date newborns, have a relatively increased risk for the development of CKD later in life. Persons with a high-risk birth and early childhood history should be watched closely in order to help detect early signs of kidney disease in time to provide effective prevention or treatment. Successful therapy is feasible for advanced CKD in childhood; there is evidence that children fare better than adults if they receive kidney replacement therapy including dialysis and transplantation, while only a minority of children may require this ultimate intervention. Because there are disparities in access to care, effort is needed so that those children with kidney disease, wherever they live, may be treated effectively, irrespective of their geographic or economic circumstances. Our hope is that World Kidney Day will inform the general public, policy-makers, and caregivers about the needs and possibilities surrounding kidney disease in childhood.

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