Transcriptomic signatures shaped by cell proportions shed light on comparative developmental biology
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- 作者：Sophie Pantalacci ; Laurent Guéguen ; Coraline Petit ; Anne Lambert…
- 关键词：Comparative transcriptomics ; Developmental biology ; Transcriptomic signature ; Temporal dynamics of gene expression ; Heterochrony ; Serial homology ; Tooth
- 刊名：Genome Biology
- 出版年：2017
- 出版时间：December 2017
- 年：2017
- 卷：18
- 期：1
- 全文大小：1888KB
- 刊物主题：Animal Genetics and Genomics; Human Genetics; Plant Genetics & Genomics; Microbial Genetics and Genomics; Bioinformatics; Evolutionary Biology;
- 出版者：BioMed Central
- ISSN：1474-760X
- 卷排序：18
文摘
BackgroundComparative transcriptomics can answer many questions in developmental and evolutionary developmental biology. Most transcriptomic studies start by showing global patterns of variation in transcriptomes that differ between species or organs through developmental time. However, little is known about the kinds of expression differences that shape these patterns.